Study uncovers early B cell developmental disorders associated with systemic lupus erythematosus

3D rendering of a B cell. Credit: Blausen.com staff (2014). “Medical gallery of Blausen Medical 2014”. WikiJournal of Medicine 1 (2). DOI:10.15347/wjm/2014.010. ISSN 2002-4436. CC BY-SA 4.0 In a study…

Immune health is all about balance – an immunologist explains why both too strong and too weak an immune response can lead to illness

For immune health, some influencers seem to think the Goldilocks philosophy of “just right” is overrated. Why settle for less immunity when you can have more? Many social media posts…

A closer look at rebel T cells: MAIT cells

The chest of an adult, showing the location and size of the adult thymus. Credit: LearnAnatomy/Wikipedia/CC BY 3.0 Scientists at La Jolla Institute for Immunology (LJI) are investigating a talented…

Measuring skin water loss found to predict anaphylaxis during food allergy tests

Change in sTEWL during OFC. (A and B) Difference between baseline TEWL and TEWL at food dose 2 or 3 (nonreactors, n = 62) or prior to epinephrine or other…

Hospital’s pioneering gene therapy aims to free patients of blood disease. Is a cure at hand?

by Lisa M. Krieger, The Mercury News Credit: Pixabay/CC0 Public Domain Born with a deadly blood disease, Clint and Alissa Finlayson’s adopted daughters—Ada, nine, and Lily, 12—are the first patients…

Study reveals how young children’s immune systems tame SARS-CoV-2

Credit: Pixabay/CC0 Public Domain New research helps explain why young children have lower rates of severe COVID-19 than adults. A study of infants and young children found those who acquired…

Infant immune systems found to have unique and effective responses to SARS-CoV-2

Credit: Cell (2023). DOI: 10.1016/j.cell.2023.08.044 Research led by the University of Tübingen, Germany, along with partners at Stanford University, Emory University and the Cincinnati Children’s Hospital Medical Center, U.S., has…

Making immunotherapy safe for AML

In a clever sleight of hand, researchers used base editing to shield healthy blood stem cells from immunotherapy, avoiding toxicity. Credit: Adobe Stock | Illustration: Sebastian Stankiewicz, Boston Children’s Hospital…

Researcher discusses how lung macrophages evolve during metastatic growth of lung colonies in a mouse model of melanoma

Credit: Unsplash/CC0 Public Domain A new editorial paper titled “A macrophage is a macrophage is a macrophage—in metastasis” has been published in Oncotarget. In this new editorial, researcher Thomas T.…

5 advances in cancer treatment

Credit: Pixabay/CC0 Public Domain QUESTION: In the past year, several family members have been diagnosed with various types of cancer, including leukemia, melanoma, breast cancer and colon cancer. In talking…