Summary: A longitudinal neuroimaging investigation published in Neurology, the medical journal of the American Academy of Neurology, demonstrates that longer lifetime estrogen exposure and hormonal therapy use are strongly tied…
Tag: Aging
Dietary Lecithin Linked to Lower Cognitive Impairment
Summary: A cross-sectional epidemiological and targeted lipidomics study of 1,917 community-dwelling older adults reveals that higher dietary intake of lecithin, a major source of phosphatidylcholine, is significantly associated with a…
Higher BMI Linked to Longer Survival After a Dementia Diagnosis
Summary: A long-term study of more than 4,500 older adults reveals that individuals who are overweight or obese when diagnosed with dementia exhibit a significantly lower risk of death than…
Comparing Current Appearance to Past Selves Harms Body Image
Summary: A new psychometric study from The Ohio State University reveals that comparing our current body to former versions of ourselves is just as harmful to mental health as comparing…
Peripheral Blood Cells Replenish Aging Human Microglia
Summary: Researchers revealed that aging leads to a massive, previously unrecognized migration of peripheral blood stem cell-derived immune cells into the human brain. The team dismantled the long-held dogma that…
Depression Triggers Volume Loss in Memory Brain Areas
Summary: Researchers identified a specific structural brain change associated with depression in older adults. Examining high-resolution MRI scans from 2,009 cognitively unimpaired adults aged 50 to 90, the team discovered…
Alzheimer Genetic Risk Scores Do Not Explain SuperAging
Summary: A new study reveals that exceptional memory in older adults is not driven simply by low inherited Alzheimer’s disease risk. The multi-center study evaluated 142 SuperAgers (adults in their…
Stress Accelerates Immune Aging by Altering the Microbiome
Summary: Researchers have demonstrated a definitive brain-gut-bone marrow axis in mice that explains this destructive link. The data reveals that chronic psychological stress suppresses key executive and emotional regions of…
Autophagy Decline in Older Moms Halts Embryo Development
Summary: Researchers unmasked a hidden metabolic mechanism that explains why advanced maternal age (AMA) impairs female fertility and reduces the success rates of assisted reproductive technology (ART). Utilizing non-targeted lipidomics,…
