Summary: Researchers uncovered a fundamental epigenetic mechanism explaining how early-life adversity permanently alters the brain’s stress response networks. The study identified that childhood trauma increases levels of the enzyme SETD7…
Category: mental health
Brain PET Scans Link Late-Onset Psychosis to Tau and Amyloid
Summary: A new study demonstrates that first-episode hallucinations and delusions appearing after age 40 are frequently driven by underlying neurodegenerative pathology. Using molecular positron emission tomography (PET) imaging, the team…
AI Models Analyze Children’s Speech to Predict Future Mental Health
Summary: Researchers demonstrated that natural language processing (NLP) models analyzing speech patterns in children aged 9 to 13 can predict the onset of mental health disorders six years later more…
Psilocybin Therapy Drives 75% PTSD Remission
Summary: The first U.S. clinical trial evaluating psilocybin-assisted therapy in military veterans with treatment-resistant post-traumatic stress disorder (PTSD) has demonstrated significant safety and clinical efficacy. The 11-week pilot trial combined…
Recall-By-Genotype for Precision Psychiatry – Neuroscience News
Summary: A new study provides a practical framework for recall-by-genotype (RbG) research within large, diverse healthcare system biobanks to advance precision psychiatry. Researchers utilized Mount Sinai’s BioMe biobank to identify…
Study Maps Motor Abnormalities Across Mental Health Spectrums
Summary: Researchers utilized the Hierarchical Taxonomy of Psychopathology (HiToP) framework to analyze self-reported motor symptoms and psychological dimensions in nearly 3,500 participants without prior formal diagnoses. The team evaluated motor…
Risk Genes for Borderline Personality Disorder Discovered
Summary: Researchers identified 11 independent genomic risk regions (loci) and 9 specific candidate genes linked to BPD development. The study establishes that common genetic variants account for 17.3% of the…
Study Maps Brain Stem Networks to Help Patients Regulate PTSD
Summary: A new study combines rodent circuitry mapping with ultra-high-field 7T human fMRI to investigate periaqueductal gray (PAG) regulation. By identifying the upstream brain regions that govern this core midbrain…
C1 Neurons Identified as Master Anxiety Switch
Summary: Researchers discovered that a specific subpopulation of epinephrine-producing cells, known as C1 neurons, act as master controllers of fear and persistent anxiety. Normally, these cells sound a brief, temporary…
When Hearing Voices Functions as a Coping Mechanism
Summary: Researchers launched a pioneering set of clinical resources, including a practical guide and a short documentary film. The project proves that hearing voices can often function as an adaptive,…
