Chronic Stress Shapes Cognitive Aging

Summary: A longitudinal study of nearly 3,900 older adults revealed that while robust social support helps shield attention from age-related decline across all demographics, it does not counteract the harmful…

Can Humor Treat Depression? – Neuroscience News

Summary: A comprehensive review of clinical psychology and neuroimaging research shows that while humor can build resilience and protect against depressive relapse, it often does more harm than good during…

Five Brain Profiles of Depression Identified

Summary: Researchers using magnetoencephalography (MEG) identified five distinct neurophysiological subtypes of major depressive disorder based on functional brain connectivity. The findings show that patients sharing the same clinical diagnosis can…

Loneliness Erases Nearly 6 Healthy Years

Summary: A massive observational study of more than 277,000 adults reveals that loneliness and social isolation significantly shorten disease-free life expectancy, stripping men of nearly six years and women of…

Nighttime Light Exposure Linked to Sleep Loss in Schizophrenia

Summary: A new study reveals that nighttime light exposure is strongly associated with objective sleep disruption in outpatients with schizophrenia, resulting in nearly an hour less total sleep per night.…

Early Stress Heightens Adult Anxiety

Summary: Researchers uncovered a fundamental epigenetic mechanism explaining how early-life adversity permanently alters the brain’s stress response networks. The study identified that childhood trauma increases levels of the enzyme SETD7…

Brain PET Scans Link Late-Onset Psychosis to Tau and Amyloid

Summary: A new study demonstrates that first-episode hallucinations and delusions appearing after age 40 are frequently driven by underlying neurodegenerative pathology. Using molecular positron emission tomography (PET) imaging, the team…

AI Models Analyze Children’s Speech to Predict Future Mental Health

Summary: Researchers demonstrated that natural language processing (NLP) models analyzing speech patterns in children aged 9 to 13 can predict the onset of mental health disorders six years later more…

Psilocybin Therapy Drives 75% PTSD Remission

Summary: The first U.S. clinical trial evaluating psilocybin-assisted therapy in military veterans with treatment-resistant post-traumatic stress disorder (PTSD) has demonstrated significant safety and clinical efficacy. The 11-week pilot trial combined…

Recall-By-Genotype for Precision Psychiatry – Neuroscience News

Summary: A new study provides a practical framework for recall-by-genotype (RbG) research within large, diverse healthcare system biobanks to advance precision psychiatry. Researchers utilized Mount Sinai’s BioMe biobank to identify…