Estrogen Exposure Shields the Aging Brain

Summary: A longitudinal neuroimaging investigation published in Neurology, the medical journal of the American Academy of Neurology, demonstrates that longer lifetime estrogen exposure and hormonal therapy use are strongly tied…

Dietary Lecithin Linked to Lower Cognitive Impairment

Summary: A cross-sectional epidemiological and targeted lipidomics study of 1,917 community-dwelling older adults reveals that higher dietary intake of lecithin, a major source of phosphatidylcholine, is significantly associated with a…

Higher BMI Linked to Longer Survival After a Dementia Diagnosis

Summary: A long-term study of more than 4,500 older adults reveals that individuals who are overweight or obese when diagnosed with dementia exhibit a significantly lower risk of death than…

Comparing Current Appearance to Past Selves Harms Body Image

Summary: A new psychometric study from The Ohio State University reveals that comparing our current body to former versions of ourselves is just as harmful to mental health as comparing…

Chronic Stress Shapes Cognitive Aging

Summary: A longitudinal study of nearly 3,900 older adults revealed that while robust social support helps shield attention from age-related decline across all demographics, it does not counteract the harmful…

Alzheimer Genetic Risk Scores Do Not Explain SuperAging

Summary: A new study reveals that exceptional memory in older adults is not driven simply by low inherited Alzheimer’s disease risk. The multi-center study evaluated 142 SuperAgers (adults in their…

Stress Accelerates Immune Aging by Altering the Microbiome

Summary: Researchers have demonstrated a definitive brain-gut-bone marrow axis in mice that explains this destructive link. The data reveals that chronic psychological stress suppresses key executive and emotional regions of…

Autophagy Decline in Older Moms Halts Embryo Development

Summary: Researchers unmasked a hidden metabolic mechanism that explains why advanced maternal age (AMA) impairs female fertility and reduces the success rates of assisted reproductive technology (ART). Utilizing non-targeted lipidomics,…

Mapping the Brain’s Resting Grid Through Menopause

Summary: A new study provided concrete evidence that the menopause transition is a critical neurological phase shift rather than a simple reproductive milestone. The two-year investigation tracked functional brain activity…

The “Goldilocks” Choice: Why Older Adults are Turning to Cannabis

Summary: Cannabis use among adults over 60 is the fastest-growing demographic in the U.S., yet their motivations and decision-making processes have largely remained a mystery. A new study reveals that…