Customizing T cell-based immunotherapies using new ‘SNAPtag’ technology

Universal adaptor SNAP-CAR and SNAP-synNotch receptor function. a A benzylguanine motif (BG) is chemically conjugated to an antibody using a benzylguanine NHS ester. The BG-antibody conjugate then covalently binds to…

Antibiotic-resistant bacteria contaminates whole ICU, shows study

Credit: Pixabay/CC0 Public Domain Carbapenem-resistant Acinetobacter baumannii (CRAB) was brought into the ICU, in Hangzhou, on multiple occasions as patients were admitted, creating a large ‘reservoir’ of the bacteria which…

Metabolic syndrome with heavy alcohol use contributes to recent surge in alcoholic liver disease-related mortality

Credit: Pixabay/CC0 Public Domain A brief research report evaluating the relationship between metabolic syndrome (MetS) and a recent increase in alcohol-associated liver disease (ALD) deaths has found that heavy alcohol…

New research reveals challenges faced by mothers living with HIV in Indonesia

Credit: Unsplash/CC0 Public Domain Living with HIV is certainly a very big deal. It has detrimental mental health impacts on people. Such impacts are even worse for mothers living with…

Domestic abuse exposure linked to increased levels of asthma and other atopic diseases

Credit: Pixabay/CC0 Public Domain Women who have suffered domestic abuse may have a higher risk of developing atopic diseases including asthma, new research has found. Published today in the Journal…

First RSV vaccine caps 60-year search to stem pervasive lung illness

Credit: Unsplash/CC0 Public Domain For 60 years, doctors and scientists searched for a vaccine against a common virus that, while sometimes deadly, is little known to the public. The hunt…

WHO declares COVID global emergency over

Credit: Pixabay/CC0 Public Domain More than three years after the coronavirus began ravaging the planet, the World Health Organization (WHO) announced Friday that the pandemic is no longer a public…

How interleukin-6 helps prevent allergic asthma and atopy by suppressing interleukin-2 signaling

Knowledge of this previously unrecognized mechanism may aid therapy for patients with interleukin-6 signaling mutations and hyper-IgE Syndrome, or HIES. Credit: University of Alabama at Birmingham The immune system has…

Study identifies features of Long COVID neurological symptoms

Credit: Unsplash/CC0 Public Domain Twelve people with persistent neurological symptoms after SARS-CoV-2 infection were intensely studied at the National Institutes of Health (NIH) and were found to have differences in…

Smart surgical implant coatings provide early failure warning while preventing infection

Smart coatings on orthopedic implants, developed at the University of Illinois Urbana-Champaign, have bacteria-killing nanopillars on one side and strain-mapping flexible electronics on the other. This could help physicians guide…