Stochasticity underlies variable outcomes in aging. Diverse molecular, cellular, and intracellular events that occur throughout the life course, here represented by the Hallmarks of Aging, manifest as declining organismal function…
Category: Health & Medicine
Scientists discover new approach to gene therapy
Credit: bioRxiv (2025). DOI: 10.1101/2025.01.13.632719 Researchers have found a promising new method for gene therapy. They successfully restarted inactive genes by bringing them closer to genetic switches on the DNA…
Patients, doctors and pharma companies set out plans to improve mental health diagnosis
To make mental health care more precise and personalized, two big changes are needed: First, the approach to care must include the latest scientific discoveries and new technologies. Second, the…
Gut microbiome composition and food insecurity linked to risk of cognitive impairment in adults
Credit: CC0 Public Domain A study led in part by Mount Sinai researchers has found a compelling link between the composition of the gut microbiome and the risk of cognitive…
High levels of antihistamine drugs can reduce fitness gains, study finds
Credit: Journal of Applied Physiology (2025). DOI: 10.1152/japplphysiol.00687.2024 For some, the word “histamine” might evoke thoughts of seasonal allergies: runny noses, scratchy throats and itchy eyes. But the molecule also…
Puberty blockers do not cause problems with sexual functioning in transgender adults, study finds
Credit: CC0 Public Domain During puberty, all kinds of hormonal changes take place in the body, which lead to the development of external sexual characteristics, such as breast growth, a…
Anal cancer screening could cut cancer deaths by up to 65% among high-risk group, experts suggest
Anal cancer has high morbidity and mortality and is preceded by the development of detectable precancerous lesions. This large study assessed the cost-effectiveness and expected benefits and harms of anal…
Despite overall progress, low birthweight rates still high in certain Indian states
Credit: Unsplash/CC0 Public Domain Despite overall progress in bringing down low birthweight numbers across India over the past 30 years, rates remain stubbornly high in certain states, with Uttar Pradesh,…
Algorithm rapidly identifies cell types to match patients with effective cancer therapies
Scientists at VCU have created a new tool called TACIT that could help doctors better understand what is happening inside the body by using advanced computer models to identify different…
Discovery of DIAL syndrome links faulty DNA repair to childhood cancer risk and chemo sensitivity
Cells lacking DIAPH1 display an inability to repair DSBs. Credit: Nature Communications (2025). DOI: 10.1038/s41467-025-59553-0 A new hereditary condition has been discovered that affects patients’ ability to repair DNA—leaving them…
