New therapy reduces reoffending in male offenders with antisocial personality disorder

Credit: Alex Green from Pexels A new psychological therapy designed by a team of UCL-led researchers has been found to reduce rates of violence and aggression among male offenders with…

Treating liver fibrosis and metabolic dysfunction-associated steatohepatitis: Research identifies novel mechanism

The proposed model for FGF21-activated PPP6C in treating liver Fibrosis and metabolic dysfunction-associated steatohepatitis. Credit: Prof. Li Yu’s group Metabolic dysfunction-associated steatohepatitis (MASH) significantly increases the risk of liver cirrhosis…

Lost tomb of Thutmose II discovered near Luxor

A joint English-Egyptian archaeological mission has discovered the tomb of Thutmose II, the fourth Pharaoh of the Eighteenth Dynasty of Egypt. Thutmose II, the son of Thutmose I and his…

AI model automatically segments MRI images, reducing radiologist workload

Example MRI scans in the training dataset. Since images were randomly sampled from clinical routine, the dataset (n = 561) contains a wide variety of different contrasts, pathologies, and image…

Early Life Stress Rewires Brain Circuits Linked to Social Motivation

Summary: New research shows that early life stress disrupts dopamine signaling, altering social motivation and behavior. Scientists found that mice raised in stressful conditions were less likely to engage in…

Depression Speeds Up Physical Illness

Summary: Adults with a history of depression develop long-term physical conditions about 30% faster than those without, according to a large study. Researchers analyzed data from over 172,000 participants and…

Prenatal Stress Hormones Alter Brain Development

Summary: Environmental factors like stress and medication exposure during pregnancy can shape brain development, but the mechanisms remain unclear. Researchers used brain organoids to study the effects of synthetic glucocorticoids,…

Trans people affirmed their gender without medical help in medieval Europe − history shows how identity transcends medicine and law

Restrictions on medical care for transgender youth assume that without the ability to medically transition, trans people will vanish. As of 2024, 26 U.S. states have banned gender-affirming care for…

Many gluten-free foods are high in calories and sugar, low on fiber and protein, and they cost more − new research

U.S. consumers often pay more for gluten-free products, yet these items typically provide less protein and more sugar and calories compared with gluten-containing alternatives. That is the key finding of…

Mapping complex interactions between sex hormones and neurological health

The brain-pituitary-ovarian axis (simplified). 4A, delta-4-androstenedione; ACh, acetylcholine; DA, dopamine; E1, estrone; E2, estradiol; FSH, follicle stimulating hormone; G, ghrelin; GnRH, gonadotropin-releasing hormone; 5-HT, 5-hydroxytryptamine (serotonin); I, insulin; K, kisspeptin;…