A single shot that could provide months-long protection against malaria has proven effective and safe in a small, early clinical trial of adults.
The shot, which contains monoclonal antibodies, would primarily be intended for infants and children in countries with the most malaria transmission, the team who conducted the trial says. These young children have the highest risk of dying from severe malaria.
In the clinical trial, 15 of 17 participants who received the monoclonal antibodies did not become infected after being exposed to mosquitoes with malaria in the lab, the researchers report in the Aug. 4 New England Journal of Medicine. All six people who did not receive the medicine developed infections.
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