A mucus-wicking robotic pill may offer a new way to deliver meds.
The multivitamin-sized device houses a motor and a cargo hold for drugs, including ones that are typically given via injections or intravenously, such as insulin and some antibiotics. If people could take such drugs orally, they could potentially avoid daily shots or a hospital stay, which would be “a huge game changer,” says MIT biomedical engineer Shriya Srinivasan.
But drugs that enter the body via the mouth face a tough journey. They encounter churning stomach acid, raging digestive enzymes and sticky slicks of mucus in the gut. Intestinal mucus “sort of acts like Jell-O,” Srinivasan says. The goo can trap drug particles, preventing them from entering the bloodstream.
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