Neuroscie
ECT Reprograms Adult Neurons into a Youthful State
Summary: Researchers engineered a highly specialized patterned stimulation protocol called REPOPS (Repeated Electroconvulsive-like Patterned Optical/Electrical Stimulation) in murine models to precisely mirror the neural activation patterns of ECT. The empirical…
GLP-1’s Reduce Binge Eating Symptoms
Summary: Findings revealed a profound therapeutic benefit: GLP-1 receptor agonists (such as semaglutide, tirzepatide, and liraglutide) do not merely drive physical weight reduction. Instead, they actively downregulate the core behavioral…
Widespread M1 Receptor Deficits in Schizophrenia Found
Summary: Researchers delivered the world’s first in vivo (in a living organism) evidence of widespread muscarinic acetylcholine M1 receptor deficits in schizophrenia. Utilizing a pioneering, highly selective PET radiotracer, the…
Gene Therapy Reverses Severe Traits of Fragile X Syndrome
Summary: Utilizing specialized adeno-associated viral (AAV) vectors to deliver functional human FMR1 directly into the central nervous system, the team successfully restored FMRP production within key cortical and subcortical regions…
Life
Nature
Newfound bat skeletons are the oldest on record
Two fossilized bat skeletons unearthed in western Wyoming represent a new species and are the oldest set of bat bones yet discovered, researchers say. The incredibly complete fossils of Icaronycteris…
Astronomy
Asteroid 2024 YR4 was Earth’s first real-life defense test
Artist’s depiction of an asteroid floating in space. Credit: NASA, ESA, CSA, N. Bartmann (ESA/Webb), Martin Kornmesser (ESA), Serge Brunier (ESO), Nick Risinger (Photopic Sky Survey) At this point in…
How do you fire someone into the sun?
Firing our villain straight at the Sun results in a big miss. Credit: Michael Brown, CC BY To point a rocket directly at the sun and hit would require great…
Cosmic ray puzzle resolved as scientists link ‘knee’ formation to black holes
LHAASO experiment. Credit: LHAASO Collaboration Milestone results released by the Large High Altitude Air Shower Observatory (LHAASO) on November 16 have solved a decades-old mystery about the cosmic ray energy…
If the supernova standard candle is wrong, it could solve the Hubble tension
An illustration showing how Baryon Acoustic Oscillations (BAOs) expand with the universe. Credit: Gabriela Secara, Perimeter Institute CC-BY-4.0 Last time I wrote about new data that overturns the standard cosmological…
