Balancing kratom’s potential benefits and risks − new legislation in Colorado seeks to minimize harm

David Bregger had never heard of kratom before his son, Daniel, 33, died in Denver in 2021 from using what he thought was a natural and safe remedy for anxiety.…

When developing countries band together, lifesaving drugs become cheaper and easier to buy − with trade-offs

Procuring lifesaving drugs is a daunting challenge in many low- and middle-income countries. Essential treatments are often neither available nor affordable in these nations, even decades after the drugs entered…

Colorado’s fentanyl criminalization bill won’t solve the opioid epidemic, say the people most affected

Colorado passed the Fentanyl Accountability and Prevention Bill in May 2022. The legislation made the possession of small amounts of fentanyl a felony, rather than a misdemeanor. Felonies are more…

Philly’s street fentanyl contains an industrial chemical called BTMPS that’s an ingredient in plastic

As much as half of the fentanyl sold on Philly’s streets contains an industrial chemical used in plastics manufacturing. That’s according to our November 2024 testing of fentanyl samples collected…

How opioid deaths tripled in Philly over a decade − and what may be behind a recent downturn

After nearly a decade of almost year-over-year increases in overdose deaths, the tide may finally be turning in Philadelphia. The Centers for Disease Control and Prevention announced in May 2024…

Your environment affects how well your medications work − identifying exactly how could make medicine better

Your genes play a major role in determining your height, hair and eye color, and skin tone, but they don’t tell the entire story of who you are. Your environment…

What are pharmacy benefit managers? A health economist explains how lack of competition drives up drug prices for everyone

Wegovy and Ozempic are weight loss drugs that promise to transform the treatment of obesity, heart disease and other chronic conditions that afflict millions of Americans. But while everyone agrees…

Drug prices improved under Biden-Harris and Trump − but not for everyone, and not enough

When it comes to drug pricing, the Trump and Biden-Harris administrations both have some very modest wins to tout. As director of the Health Outcomes, Policy, and Evidence Synthesis group…

Philly residents with opioid addiction get medication from the ‘bupe bus’ − creating a path for treatment

A mobile team offering medication treatment to people with opioid use disorder showed promise in getting patients in Philadelphia to return for follow-up visits, according to a peer-reviewed study I…

Nitazenes found in 5 overdose deaths in Philly – here’s what they are and why they’re so deadly

The Philadelphia Medical Examiner’s Office found that nitazenes, a synthetic opioid up to 40 times more powerful than fentanyl, were connected to at least five overdose deaths in Philadelphia in…