Summary: Researchers uncovered how Alzheimer’s Disease (AD) impacts COVID-19 outcomes through changes in the olfactory mucosal cells. Their study focused on individuals with AD who experienced exacerbated COVID-19 symptoms. Using…
Tag: Genetics
Brain Cell Genetics Illuminate Alzheimer’s Disease Pathways
Summary: Researchers made a significant advance in understanding Alzheimer’s disease (AD) by pinpointing how specific brain cells contribute to different stages of the disease. Employing single nucleus RNA sequencing, they…
Research examines how protein aggregates can trigger neurodegenerative diseases
Credit: Pixabay/CC0 Public Domain Neurodegenerative diseases are characterized by the deposition of clumped proteins in the brain and progressive neuronal cell death. Although the causal link between protein aggregates and…
Peptide PACAP’s Key Role in Alcohol Addiction
Summary: Alcohol, the world’s most common addictive substance, leads to $249 billion in annual costs and 88,000 deaths in the U.S. Alcohol use disorder affects millions but is under-treated. Researchers…
RNA’s Pivotal Role in Fear Memory and PTSD Treatment
Summary: Researchers have revealed a groundbreaking role of RNA in fear-related learning and memory. Their study shows how noncoding RNA Gas5 influences neuronal excitability, impacting learning and memory processes. Another…
Study identifies familial germline EGFR T790M variant in lung cancer
A new familial lung cancer caused by an inherited mutation in EGFR has been described in a study published online Oct. 23 in the Journal of Clinical Oncology. Geoffrey R.…
Genetics of nearby healthy tissue may help catch lung cancer’s return
Credit: Pixabay/CC0 Public Domain Genetic information collected from seemingly healthy tissue near lung tumors may be a better predictor of whether cancer will come back after treatment than analysis of…
Promising Targets Discovered for Rare Brain Disorder PSP
Summary: Researchers have identified new therapeutic targets for progressive supranuclear palsy (PSP), an incurable brain disorder with symptoms mimicking Parkinson’s and dementia. The study focused on RNA sequencing from brain…
New Gene Link to Treatment-Resistant Depression
Summary: Researchers discovered a gene, LHPP, that interacts with stress and plays a pivotal role in treatment-resistant Major Depressive Disorder (MDD) using an animal model. This groundbreaking study underscores the…
Mosaic chromosomal alterations study provides valuable insights into drivers of cancer risk
Genomic distribution of autosomal mCAs. a, mCA calls across autosomal chromosomes. b, Histogram of mCA calls across the genome for each genetic ancestry group. The X axis is shown in…
