Credit: Pixabay/CC0 Public Domain Identifying people at high risk of chronic disease means that they can be targeted with prevention measures before they become sick. Polygenic risk scores, where genomic…
Tag: Genetics
The use of AI in eye scans may help improve diagnosis of inherited disease of the retina
Credit: Pixabay/CC0 Public Domain Inherited retinal diseases (IRDs), single-gene disorders affecting the retina, are very difficult to diagnose since they are uncommon and involve changes in one of many candidate…
Hitching a Ride: mRNA’s Transport System in Brain Cells Revealed
Summary: Researchers made significant advancements in understanding how mRNA is distributed in brain cells. They discovered that a protein complex called FERRY aids Early Endosomes (EEs) to carry mRNAs to…
Unlocking Addiction Risk: Genetic Test Could Shape Future Prevention Strategies
Summary: A new study hints at the potential of utilizing genetic test results to improve addiction prevention and treatment strategies. The study involved 325 college students who were given varying…
Top 5 Neuroscience News Stories of the Week
Summary: This week, research teams from around the globe shared their remarkable findings from the field of neuroscience. Discoveries ranged from unraveling how Botox breaches neurons, to a study finding…
Gene Therapy Reverses Age-Related Hearing Loss
Summary: Researchers successfully demonstrated the efficacy of adeno-associated virus (AAV) vectors in reversing genetic hearing loss in aged animal models. The scientists developed a mature mouse model with a mutation…
Shared Genetics for Cannabis Use and Psychiatric Disorders
Summary: Researchers discovered shared genetic underpinnings for cannabis use and psychiatric disorders like schizophrenia and bipolar disorder. Employing advanced statistical modeling, the study revealed a complex interplay of genetic variants…
A proposed new metric to quantify genetic dissimilarities between an individual and a training population
Illustration of population-level versus individual-level PGS accuracy. a, Discrete labeling of GIA with PCA-based clustering. Each dot represents an individual. The circles represent arbitrary boundaries imposed on the genetic ancestry…
Researchers find link between obesity and blood cancer
Credit: Unsplash/CC0 Public Domain Indiana University School of Medicine researchers studying clonal hematopoiesis of indeterminate potential (CHIP), a blood condition that may increase the risk of blood cancer, discovered that…
Schizophrenia Risk Genes: Placenta’s Role May Outweigh Brain’s
Summary: In a paradigm shift, researchers found over 100 genes associated with schizophrenia risk operate primarily through their role in the placenta, rather than the developing brain. The research emphasizes…
