Summary: Researchers made a groundbreaking discovery about the maturation process of adult-born neurons in the brain, highlighting the critical role of mitochondrial fusion in these cells. Their study shows that…
Tag: Genetics
Biological mechanism discovered that could lead to new treatments for neurological disorders and cancers
Credit: Pixabay/CC0 Public Domain The lab of Yongchao C. Ma, Ph.D., at Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago has discovered a…
Genetic causes of cerebral palsy uncovered through whole-genome sequencing
Credit: Unsplash/CC0 Public Domain A Canadian-led study has identified genes which may be partially responsible for the development of cerebral palsy. Cerebral palsy (CP), a condition that affects the development…
Hereditary Alzheimer’s Transmitted Via Bone Marrow Transplants
Summary: Alzheimer’s disease, traditionally seen as a brain-centric condition, may have systemic origins and can be accelerated through bone marrow transplants from donors with familial Alzheimer’s to healthy mice. A…
Epigenetics is of critical importance in autoimmune-related skin diseases, says study
Credit: Lingyu Gao, Qianjin Lu The central dogma proposed that genetic information predominantly transfers from DNA to RNA during gene expression to make a functional product protein. This absolute theory…
New review on p53 biology and reactivation in blood cancers
A simplified scheme of p53 regulation in cells upon stress and the drugs currently evaluated in clinical trials for p53 reactivation for improved therapy in MDS and AML. Credit: Biomarker…
Scientists identify Achilles heel of lung cancer protein
Rendering of interface in the mutant EGFR studied that was shown to be critical for EGFR-driven tumor growth. The K946E mutation shown in red was used by the team to…
Molecular Alterations in Brain Tissue Provide Clues to Suicidal Ideation
Summary: Researchers have identified molecular alterations in the blood and brain tissues of individuals who committed suicide, offering new insights into susceptibility factors and therapeutic targets. The study analyzed genetic,…
Unlocking Synaptic Mysteries: The Role of FAM81A Protein
Summary: Researchers have identified a critical protein, FAM81A, that plays a pivotal role in forming postsynaptic protein agglomerations, essential for synaptic function in the brain. By analyzing 35 previous studies,…
