Gene Clusters Reveal Brain Link to Anxiety Disorders

Summary: Researchers made a significant breakthrough in understanding the genetic basis of anxiety disorders (ADs), which affect over 280 million people globally. By analyzing the spatiotemporal transcriptomic data of AD-associated…

Do genes that code athletic heart enlargement carry a risk of future heart problems?

Credit: Pixabay/CC0 Public Domain A new landmark study involving 281 elite athletes from Australia and Belgium has revealed one in six have measurements that would normally suggest reduced heart function.…

Alzheimer’s Alters COVID-19 Response in Olfactory Cells

Summary: Researchers uncovered how Alzheimer’s Disease (AD) impacts COVID-19 outcomes through changes in the olfactory mucosal cells. Their study focused on individuals with AD who experienced exacerbated COVID-19 symptoms. Using…

Brain Cell Genetics Illuminate Alzheimer’s Disease Pathways

Summary: Researchers made a significant advance in understanding Alzheimer’s disease (AD) by pinpointing how specific brain cells contribute to different stages of the disease. Employing single nucleus RNA sequencing, they…

Research examines how protein aggregates can trigger neurodegenerative diseases

Credit: Pixabay/CC0 Public Domain Neurodegenerative diseases are characterized by the deposition of clumped proteins in the brain and progressive neuronal cell death. Although the causal link between protein aggregates and…

Peptide PACAP’s Key Role in Alcohol Addiction

Summary: Alcohol, the world’s most common addictive substance, leads to $249 billion in annual costs and 88,000 deaths in the U.S. Alcohol use disorder affects millions but is under-treated. Researchers…

RNA’s Pivotal Role in Fear Memory and PTSD Treatment

Summary: Researchers have revealed a groundbreaking role of RNA in fear-related learning and memory. Their study shows how noncoding RNA Gas5 influences neuronal excitability, impacting learning and memory processes. Another…

Study identifies familial germline EGFR T790M variant in lung cancer

A new familial lung cancer caused by an inherited mutation in EGFR has been described in a study published online Oct. 23 in the Journal of Clinical Oncology. Geoffrey R.…

Genetics of nearby healthy tissue may help catch lung cancer’s return

Credit: Pixabay/CC0 Public Domain Genetic information collected from seemingly healthy tissue near lung tumors may be a better predictor of whether cancer will come back after treatment than analysis of…

Promising Targets Discovered for Rare Brain Disorder PSP

Summary: Researchers have identified new therapeutic targets for progressive supranuclear palsy (PSP), an incurable brain disorder with symptoms mimicking Parkinson’s and dementia. The study focused on RNA sequencing from brain…