Overcoming the limits of immunotherapies

Karl Petri (left) is setting up an Emmy Noether research group at the University Hospital of Würzburg with the support of the German Research Foundation. Alexandre Trubert (centre) and Leon…

Australia launches landmark peanut allergy treatment for babies

Credit: CC0 Public Domain Australian children with potentially deadly peanut allergies will be offered life-saving treatment in a nationwide program touted as a world first. Eligible babies will receive daily…

Research shows spike gene mutations do not correlate with increased SARS-CoV-2 variant severity

A visual representation of the novel in silico methodology used in the study: prediction of protein structure, molecular docking simulations, and statistical analysis of computational metrics. Credit: UNC Charlotte New…

Targeted drug treatment leads tumor cells to imitate viral infection, researchers discover

mIDH1 inhibition restores immune surveillance. Credit: Science (2024). DOI: 10.1126/science.adl6173 A number of cancers, including certain brain and liver tumors, as well as myeloid leukemias, are driven by mutations in…

Distinct T-cell signatures observed at different stages of type 1 diabetes development

Credit: CC0 Public Domain A study conducted at the University of Eastern Finland found distinct signatures in CD8+ T cells in blood samples from children with newly diagnosed type 1…

Scientists create first mouse model with complete, functional human immune system

Left, malar rash in a (huNSGW41-derived) Lupus THX mouse (three weeks after pristane injection). Middle, serum antinuclear IgGs (scale bar, 20 μm) and kidney immunopathology (H&E and anti-huIgG immunofluorescence; scale bar,…

New insights into metabolic and immune pathway interactions in obesity

A diagrammatic illustration represents the proposed model. The energy sensor AMPK becomes less active under energy overload conditions, which leads to hypophosphorylation of TBC1D1. Hypophosphorylated TBC1D1 is more active and…

Scientists discover new T cells and genes related to immune disorders

A newly developed method called ReapTEC allowed the discovery of thouands of active bidirectional enhancers. Further anaylis of GWAS data revelaed that various immune-mediated diseases, like multipkle sclerosis and rheumatoisd…

New therapy strengthens the immune system’s counterattack on skin cancer

Stained electron micrograph of a T cell. Scientists have shown in laboratory experiments that they are able to create a large number of the T cells that are capable of…

Study suggests staying current with COVID-19 vaccinations helps combat emerging variants

A COVID-19 vaccine is prepped at an OHSU clinic. New research from OHSU reveals a strong immune response to an updated vaccine in the fall of 2023, suggesting a clear…