A diagrammatic illustration represents the proposed model. The energy sensor AMPK becomes less active under energy overload conditions, which leads to hypophosphorylation of TBC1D1. Hypophosphorylated TBC1D1 is more active and…
Tag: Immunology
Scientists discover new T cells and genes related to immune disorders
A newly developed method called ReapTEC allowed the discovery of thouands of active bidirectional enhancers. Further anaylis of GWAS data revelaed that various immune-mediated diseases, like multipkle sclerosis and rheumatoisd…
New therapy strengthens the immune system’s counterattack on skin cancer
Stained electron micrograph of a T cell. Scientists have shown in laboratory experiments that they are able to create a large number of the T cells that are capable of…
Study suggests staying current with COVID-19 vaccinations helps combat emerging variants
A COVID-19 vaccine is prepped at an OHSU clinic. New research from OHSU reveals a strong immune response to an updated vaccine in the fall of 2023, suggesting a clear…
Researchers explore diagnostic role of the systemic inflammation index
Credit: Unsplash/CC0 Public Domain A routine blood test that measures a patient’s inflammation levels could improve the early diagnosis and management of a wide range of debilitating autoimmune diseases. The…
Researchers identify new way to inhibit immune cells that drive allergic asthma
Activation of ILC2s causes inflammation in mouse lungs (left), but this is reduced by treatment with Yoda1 to stimulate Piezo1 channels (right). Credit: (2024). DOI: 10.1084/jem.20231835 Researchers at the Keck…
Epigenetics is of critical importance in autoimmune-related skin diseases, says study
Credit: Lingyu Gao, Qianjin Lu The central dogma proposed that genetic information predominantly transfers from DNA to RNA during gene expression to make a functional product protein. This absolute theory…
Is your blood aging your brain? It might increase your dementia risk
Credit: Unsplash/CC0 Public Domain By 2050, the global population of adults 60 and older will approximately double, leading to upward of 153 million dementia cases. That’s why University College Cork…
CARv3-TEAM-E T-cell treatment beneficial for recurrent glioblastoma
For patients with recurrent glioblastoma, treatment with chimeric antigen receptor (CAR) T-cells engineered to target the epidermal growth factor receptor (EGFR) variant III tumor-specific antigen, in addition to the wild-type…
What’s in tattoo ink? My team’s chemical analysis found ingredients that aren’t on the label and could cause allergies
Credit: Pixabay/CC0 Public Domain Tattoos are an incredibly common form of permanent self-expression that date back thousands of years. Most tattoo artists follow strict health and sanitation regulations, so you…
