Could a monthly treatment prevent fentanyl overdoses? Scientists are working on it

Anti-opioid efficacy of CSX-1004 in mice. Credit: Nature Communications (2023). DOI: 10.1038/s41467-023-43126-0 Scientists have developed an antibody treatment that shows promise in blocking the potentially deadly effects of fentanyl for…

New research suggests cellular stress in the placenta may be possible cause of preeclampsia

Credit: CC0 Public Domain Preeclampsia is a mysterious condition that occurs in about one of 10 pregnancies without any early warning signs. After 20 weeks or more of normal blood…

Measuring skin water loss found to predict anaphylaxis during food allergy tests

Change in sTEWL during OFC. (A and B) Difference between baseline TEWL and TEWL at food dose 2 or 3 (nonreactors, n = 62) or prior to epinephrine or other…

First in human trial of new drug raises hopes for patients with relapsed blood cancer

Credit: Unsplash/CC0 Public Domain A new targeted drug, studied by researchers at The Ohio State University Comprehensive Cancer Center—Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC—James),…

Horseshoe crab blood is vital for testing intravenous drugs, but new synthetic alternatives could mean pharma won’t bleed this unique species dry

If you have ever gotten a vaccine or received an intravenous drug and did not come down with a potentially life-threatening fever, you can thank a horseshoe crab (Limulus polyphemus).…

Benefits of psychedelics in obsessive-compulsive disorder: In search of evidence

Credit: Paris Brain Institute In recent years, interest in psychedelics and their possible benefit in treating psychiatric illnesses has been revived. Expectations are high, especially in obsessive-compulsive disorder, where patients’…

Nobel in medicine goes to two scientists whose work enabled creation of mRNA vaccines against COVID-19

Katalin Kariko, speaks after receiving, together with six other scientists, the Princess of Asturias Award for Technical & Scientific Research 2021 from Spain’s Princess of Asturias Leonor, at a ceremony…

How new software is changing our understanding of human brain development

A team including researchers at the University of Washington compared MRIs from 300 babies using new software to compare their brains’ white matter and discovered that myelin, a part of…

Hope for new therapy to stop advanced skin cancer

Morphological effects of P16P1 observed for melanoma cells but not fibroblasts. Representative phase-contrast images of cells after 5 days of growth with or without P16P1. (A–C) 451Lu melanoma cells with vehicle…

Gene-tweaked stem cells offer hope against sickle cell disease

A type of gene therapy that precisely “edits” a key bit of DNA might offer a new way to treat sickle cell disease—a painful inherited condition that largely strikes Black…