Research team achieves near-perfect bone healing with new multi-leveled scaffold

(a) Schematic representation of the (a) bone structure and its composition ranging from nanometers to micrometers and (b) development of biomimetic scaffolds containing the various steps for preparing a combinatorial…

For advanced, HER2-amplified bile duct cancers, antibody treatment trial shows promising results

Memorial Sloan Kettering gastrointestinal oncologist Dr. James Harding. Credit: Memorial Sloan Kettering Cancer Center Bile duct cancers are uncommon and aggressive types of gastrointestinal cancer. They include cholangiocarcinomas, which can…

Gas-releasing adjuvant improves efficacy of photothermal therapy for cancer

A nanoplatform based on copper sulfide (ADT@CuSNDs) that is able to remodel the tumor energy via hydrogen sulfide (H2S) mediation was developed to sensitize the tumor to mild photothermal therapy…

Effects of zoledronic acid on senescence and SASP markers

Zoledronic acid has senolytic effects in human lung fibroblast IMR90 cells. Credit: 2023 Samakkarnthai et al. A new research paper, titled “In vitro and in vivo effects of zoledronic acid…

How studying cell movement during embryonic development may offer new insights into cancer metastasis

Under the microscope, MSK scientists studied how cells in a mouse embryo (green) move out and break away from their original tissue by contracting their surfaces (red). Studying this process,…

Study finds inhaling ethanol can disable influenza A in mice

The study found that mice treated with ethanol vapor are protected from lethal respiratory infections caused by the influenza A virus. Credit: Dr. Miho Tamai and Prof. Hiroki Ishikawa (OIST)…

The underestimated risk factor for mortality

Effect decomposition of the mediation analysis using a counterfactual framework. Total Association: refers to the total effect of renal hyperfiltration on mortality, including both direct and indirect pathways. Controlled Direct…

Study reveals mechanism by which a circadian clock molecule leads to lung fibrosis

Decreased REV-ERBα protein abundance and increased protein levels of COL1A1 and LOX in IPF lungs compared to healthy control. Healthy control and IPF formalin fixed-paraffin embedded (FFPE) lung samples were…

Unconscious biases continue to hold back women in medicine, but research shows how to fight them and get closer to true equity and inclusion

If you work at a company, university or large organization, you’ve probably sat through a required training session meant to fight gender and racial discrimination in the workplace. Employers increasingly…