Dual-Targeting Drug Halts Tau Accumulation in Alzheimer’s

Summary: Scientists have developed a drug that targets both major aggregation-promoting sites of the Tau protein, a key player in Alzheimer’s disease. This peptide inhibitor, RI-AG03, effectively prevents Tau buildup…

Alzheimer’s Drug Faces Scrutiny Over Safety, Efficacy Concerns

Summary: The FDA-approved Alzheimer’s drug donanemab is under scrutiny due to concerns about its effectiveness and safety, according to an investigation. The study highlights multiple patient deaths during trials, design…

Tau Levels Predict Memory Loss in Alzheimer’s

Summary: Alzheimer’s disease (AD) progression varies based on the presence of tau and amyloid-beta (Aβ) proteins in the brain. Patients with high levels of both tau and Aβ experience rapid…

Tau May Protect Brain Cells from Oxidative Damage

Summary: Researchers have discovered that the Tau protein, often linked to neurodegenerative diseases like Alzheimer’s, also has a protective role in the brain. Tau helps combat oxidative stress by aiding…

Does Multiple Sclerosis Lower Dementia Risk?

Summary: Research has revealed that individuals with multiple sclerosis (MS) are significantly less likely to exhibit the molecular signs of Alzheimer’s disease, suggesting a protective element in MS that could…

What links aging and disease? A growing body of research says it’s a faulty metabolism

Aging is a biological process that no one can avoid. Ideally, growing old should be a time to relax and enjoy the fruits of your labor. Aging also has a…

Glial Cells Play Key Role in Alzheimer’s Development

Summary: New research reveals that glial cells, specifically oligodendrocytes, produce amyloid beta, a protein linked to Alzheimer’s disease, challenging the long-held belief that neurons are the sole contributors. This discovery…

Anxiety Raises Dementia Risk – Neuroscience News

Summary: A new study reveals that chronic and new anxiety are linked to a higher risk of dementia, while resolved anxiety shows no such association. Following 2,132 Australian individuals for…

Study Reveals Structure of Alzheimer’s Molecules in Human Brain

Summary: In a groundbreaking study, scientists have determined the structure of molecules within a human brain affected by Alzheimer’s disease. Using cryo-electron tomography and fluorescence microscopy, researchers created 3D maps…

Family caregivers can help shape the outcomes for their loved ones – an ICU nurse explains their vital role

The floor nurse had just told me that my new patient – let’s call her Marie – would not stop screaming. Marie landed in the intensive care unit where I…