Dementia Risk Reduced by 25% with Specific Type of Brain Exercise

Summary: Results from the long-term ACTIVE study reveal that a specific type of cognitive exercise can significantly reduce the risk of dementia for up to two decades. The study, which…

New Drug Target Could Freeze Alzheimer’s in Its Tracks

Summary: Researchers discovered a powerful new drug target that could revolutionize how we treat Alzheimer’s disease. By focusing on an enzyme called IDOL, researchers found they could substantially reduce the…

Hippocampus Predicts Rewards by Reorganizing Memories

Summary: A new preclinical study reveals that the hippocampus does more than just store memories; it actively reorganizes them to predict future rewards. By tracking brain activity over several weeks,…

Brain Stimulation Method Can Evaluate Consciousness in Alzheimer’s Disease

Summary: A new study reports that a brain complexity measure, calculated by recording EEG signals after a magnetic stimulation pulse, is significantly reduced in people with Alzheimer’s disease. This method,…

Blocking a Key Protein Greatly Reduces Alzheimer’s Damage

Summary: New findings show that removing Centaurin-α1, a protein elevated in Alzheimer’s disease, significantly reduces inflammation, plaque buildup, and cognitive deficits in a well-established mouse model. Eliminating this protein normalized…

Americans are unprepared for the expensive and complex process of aging – a geriatrician explains how they can start planning

Hollywood legend Gene Hackman and his wife, Betsy Arakawa, were found dead in their home in February 2025. Hackman had been living with Alzheimer’s and depended on Arakawa as his…

How to keep dementia from robbing your loved ones of their sense of personhood – tips for caregivers

Every three seconds, someone in the world develops dementia. There are over 6 million people living with dementia in the U.S. and 57 million globally. These figures will only increase…

Alzheimer’s Study Finds Blood-Brain Barrier Largely Intact

Summary: A new study suggests that the blood-brain barrier (BBB) remains intact in a widely used mouse model of Alzheimer’s disease. Using a tracer molecule and advanced analysis, scientists found…

Vaccines hold tantalizing promise in the fight against dementia

Over the past two centuries, vaccines have been critical for preventing infectious diseases. The World Health Organization estimates that vaccination prevents between 3 million and 5 million deaths annually from…

Tiny Brain Region Orchestrates How We Segment and Remember Life Events

Summary: Our memories don’t flow like a continuous stream—they’re divided into meaningful events, thanks to a tiny brain region called the locus coeruleus. New research shows this region acts like…