New insights into metabolic and immune pathway interactions in obesity

A diagrammatic illustration represents the proposed model. The energy sensor AMPK becomes less active under energy overload conditions, which leads to hypophosphorylation of TBC1D1. Hypophosphorylated TBC1D1 is more active and…

Drugs that kill ‘zombie’ cells may benefit some older women, but not all, study finds

Credit: CC0 Public Domain Drugs that selectively kill senescent cells may benefit otherwise healthy older women but are not a “one-size-fits-all” remedy, Mayo Clinic researchers have found. Specifically, these drugs…

Acupuncture reduces hot flashes in breast cancer therapy patients, study finds

Credit: Unsplash/CC0 Public Domain In a pooled analysis of three clinical trials, acupuncture significantly reduced hot flashes and other hormonal side effects of endocrine therapy taken by women with breast…

Arm fat may reveal women and men at risk of spinal fracture

Credit: cottonbro studio from Pexels Measuring the total mass of fat in the arms could potentially predict which women and men over 50 are at risk of spinal fracture, according…

Human muscle map reveals how we try to fight effects of aging at cellular and molecular levels

Skeletal muscle fibers. Credit: Berkshire Community College Bioscience Image Library / Public domain How muscle changes with aging and tries to fight its effects is now better understood at the…

Popular diabetes drugs do not increase thyroid cancer risk, study suggests

Credit: CC0 Public Domain Drugs known as GLP-1 analogs have become increasingly popular to treat diabetes and obesity, but there have been concerns that they might increase the risk of…

Male hormonal birth control? It may be closer than you think

The hormonal gel is applied to the shoulders, and Treviño made it part of his morning routine. Credit: Karin Higgins/UC Davis Matthew Treviño and Emily Fletcher are self-described DINKWADs—double income, no…

Fasting-like diet lowers risk factors for disease, reduces biological age in humans: Study

Credit: Pixabay/CC0 Public Domain Cycles of a diet that mimics fasting can reduce signs of immune system aging, as well as insulin resistance and liver fat in humans, resulting in…

Frog embryo study helps scientists unravel the human birth anomaly of intestinal malrotation

A transverse section through the Xenopus tadpole intersects multiple loops of the rotated intestine. Credit: Julia Grzymkowski How does our intestine, which can be at least 15 feet long, fit…

Study reveals key mechanism behind obesity-related metabolic dysfunction

These colored streaks are mitochondrial networks within fat cells. Researchers from UC San Diego discovered that a high-fat diet dismantles mitochondria, resulting in weight gain. Credit: UC San Diego Health…