Study Reveals Structure of Alzheimer’s Molecules in Human Brain

Summary: In a groundbreaking study, scientists have determined the structure of molecules within a human brain affected by Alzheimer’s disease. Using cryo-electron tomography and fluorescence microscopy, researchers created 3D maps…

Researchers map the effects of all potential changes in key cancer gene

Function scores capture fitness effects mediated at both the transcript and protein 457 level. Credit: Megan Buckley et al Researchers at the Francis Crick Institute have mapped all the possible…

Oxytocin’s Link to Obesity and Postnatal Depression

Summary: A new study has identified the TRPC5 gene as a cause of obesity, behavioral issues, and postnatal depression. Researchers found that missing or impaired TRPC5 genes disrupt oxytocin neurons,…

Kidneys from Black donors are more likely to be thrown away − a bioethicist explains why

As one of the leading causes of death in the U.S., kidney disease is a serious public health problem. The disease is particularly severe among Black Americans, who are three…

Genetic testing cannot reveal the gender of your baby − two genetic counselors explain the complexities of sex and gender

Gender reveal parties are best known as celebrations involving pink and blue, cake and confetti, and the occasional wildfire. Along with being social media hits, gender reveals are a testament…

Study uncovers multiple molecular subgroups in liver cancer with most aggressive driving clinical outcomes

Credit: Journal of Hepatology (2024). DOI: 10.1016/j.jhep.2024.05.017 A study led by clinician-scientists and scientists from the National Cancer Centre Singapore (NCCS) and A*STAR’s Genome Institute of Singapore (GIS) has discovered…

Human muscle map reveals how we try to fight effects of aging at cellular and molecular levels

Skeletal muscle fibers. Credit: Berkshire Community College Bioscience Image Library / Public domain How muscle changes with aging and tries to fight its effects is now better understood at the…

Learning and Memory Formation’s Molecular Basis

Summary: Researchers developed a new platform to explore dendritic translation’s role in memory formation and its implications for intellectual disorders. By employing a novel method named TurboID, researchers uncovered a…

Powering Brain Repair: Mitochondria Key to Neurogenesis

Summary: Researchers made a groundbreaking discovery about the maturation process of adult-born neurons in the brain, highlighting the critical role of mitochondrial fusion in these cells. Their study shows that…

Biological mechanism discovered that could lead to new treatments for neurological disorders and cancers

Credit: Pixabay/CC0 Public Domain The lab of Yongchao C. Ma, Ph.D., at Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago has discovered a…