New immunotherapy platform has increased potential to target cancer cells

Credit: Unsplash/CC0 Public Domain Researchers from Children’s Hospital of Philadelphia (CHOP) and Stanford University have revealed the molecular structure of TRACeR-I, a protein platform for reprogramming immune responses. A better…

Scientists find cause of rare devastating, autoimmune disease in Puerto Ricans—but also find potential treatment

DNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIH A rare autoimmune condition with a tongue-twister of a name may impact people of Puerto…

Glioblastoma treatment shows promise in mouse study

GAD activity in immunocompromised setting. Credit: Nature (2024). DOI: 10.1038/s41586-024-08224-z Memorial Sloan Kettering Cancer Center-led researchers have identified a small molecule called gliocidin that kills glioblastoma cells without damaging healthy…

Clinical microbiologist explains why you should never kiss a baby

Credit: Unsplash/CC0 Public Domain There is a cognitive bias called “the curse of knowledge” (sometimes also called “the curse of expertise”). It happens when you incorrectly assume that everyone knows…

New study shows how salmonella tricks gut defenses to cause infection

Colorized SEM (scanning electron micrograph) of the foodborne pathogen Salmonella enteritidis. Blue is growth medium. Picture is colored in false colors to illustrate difference. Photo by Jean Guard, ARS. Credit:…

Increased psoriasis risk found in cancer patients treated with immune checkpoint inhibitors

Credit: Estzer Miller on Pixabay Researchers from the National Defense Medical Center in Taiwan have identified an increased risk of psoriasis in patients with cancer undergoing immune checkpoint inhibitor (ICI)…

No evidence for belief that nut allergens spread through aircraft ventilation systems, say experts

Credit: Pixabay/CC0 Public Domain There is no evidence for the commonly held belief that nut allergens can be spread through aircraft ventilation systems, say allergy and aviation medicine specialists in…

In depth analysis explains why preschoolers are less likely to develop severe COVID-19

Outline of the study for the detection of SARS-CoV-2-reactive CD4+ T cells in different groups of patients. Credit: Science Translational Medicine (2024). DOI: 10.1126/scitranslmed.adl1997 Five years ago, at the outset…

Harnessing natural killer T cells to advance cancer immunotherapy for solid tumors

CAR-NKT cells target tumor cells in vitro. a, Representative flow cytometry plots illustrating the purity of NKT cells isolated from the spleen of iVα14-Jα18 transgenic mice, n = 12 with similar results.…

Researchers identify role of Parkinson’s-related protein in cancer and T cell activation

Credit: Journal of Clinical Investigation (2024). DOI: 10.1172/JCI180983 A team from the Wistar Institute has demonstrated the role of Parkin—a protein implicated in Parkinson’s disease—in the body’s innate immune response…