Identification of HLA-E restricted SARS-CoV-2-specific CD8 cells. A, Representative graphs showed the gating strategy to analyze tetramer positive cells. Live CD3+CD4–CD8+ cells were gated and CD56–CD94– cells were selected for…
Tag: Immunology
New method reveals insights into interplay between immune system and tumors
Single cell genomics reveals multiple human immune cell types in tumors and blood of autologous MISTRG6 PDX mice, including innate immune cell types present in the TME. (A) Schematic representation…
How to tell if symptoms are due to allergies, the common cold, the flu, or COVID-19
Early symptoms of viral infections and allergies can be similar, though allergies can cause itchy eyes, which is less common in viral infections. Also, fevers tend to signify infections. Credit:…
What happens in our body when we encounter and fight off a virus like the flu, SARS-CoV-2 or RSV?
Credit: Shutterstock Respiratory viruses like influenza virus (flu), SARS-CoV-2 (which causes COVID) and respiratory syncytial virus (RSV) can make us sick by infecting our respiratory system, including the nose, upper…
Pitt study points to new opportunities for HIV treatment
HIV infecting a human cell. Credit: NIH Sometimes in science, answers come serendipitously, where researchers aren’t expecting to find them. That’s what happened to Cristian Apetrei, Ivona Pandrea and their…
Study proposes new bioinformatic approach to design better vaccines
Credit: National Cancer Institute A new paper in Biology Methods & Protocols, published by Oxford University Press, shows it may be possible to design vaccines that will induce a stronger…
Early peanut introduction gaining traction among US parents, but more work needed
Credit: CC0 Public Domain In 2017, the National Institutes of Health (NIH) announced a dramatic reversal in its approach to peanut-allergy prevention, recommending parents expose their infants as young as…
Atypical infections in chronic sinusitis: Thinking outside the box
CT-scan in a sagittal section showing a mucosal swelling and obstruction of the maxillary sinus due to anaspergilloma (Contrast medium enhancement). Credit:Oncoscience (2023). DOI: 10.18632/oncoscience.576 A new research perspective was…
Enigmatic immune cells help to avoid harmful allergens
Mast cells and IgE promote immunity of avoidance. Model of mast-cell-mediated avoidance behavior in the framework of type 2 immunity. Barrier damage facilitates entry of antigens (for instance, occupational and…
Wider search needed to improve outcomes for eosinophilic food allergy, says study
Image created with BioRender. Credit: Cincinnati Children’s The good news: a monoclonal antibody treatment called benralizumab proved quite effective in a clinical trial at depleting the number of eosinophils found…
