Credit: CC0 Public Domain In 2017, the National Institutes of Health (NIH) announced a dramatic reversal in its approach to peanut-allergy prevention, recommending parents expose their infants as young as…
Tag: Immunology
Atypical infections in chronic sinusitis: Thinking outside the box
CT-scan in a sagittal section showing a mucosal swelling and obstruction of the maxillary sinus due to anaspergilloma (Contrast medium enhancement). Credit:Oncoscience (2023). DOI: 10.18632/oncoscience.576 A new research perspective was…
Enigmatic immune cells help to avoid harmful allergens
Mast cells and IgE promote immunity of avoidance. Model of mast-cell-mediated avoidance behavior in the framework of type 2 immunity. Barrier damage facilitates entry of antigens (for instance, occupational and…
Wider search needed to improve outcomes for eosinophilic food allergy, says study
Image created with BioRender. Credit: Cincinnati Children’s The good news: a monoclonal antibody treatment called benralizumab proved quite effective in a clinical trial at depleting the number of eosinophils found…
Mapping the development of infection-fighting immune cells
Cytotoxic T cell (purple) deciding whether to become a memory cell (blue) or effector cell (pink) subtype. The cBAF complex (green) and Arid1a subunit open the doors for both cell…
Immune cell movement worse in older females, mice study finds
Myeloid immune cells alongside red blood cells in an electron micrograph of human blood. Credit: National Cancer Institute According to a new study, older female mice had more immune cells entering…
Pumping the brakes on autoimmune disease
This visualization shows BTLA being recognized by the antibody LY3361237. Credit: Carl Ware/Sanford Burnham Prebys Researchers at Sanford Burnham Prebys, collaborating with scientists from Eli Lilly and Company, have revealed…
More depressed patients than previously estimated could have increased activation of their immune system
Credit: Unsplash/CC0 Public Domain New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London has used an assessment of gene expression involved in the immune…
One step closer to eliminating latency, the real challenge in combating HIV
Graphical abstract of Shclafen 12 activity. Credit: Pompeu Fabra University An international study led by MELIS-UPF researchers from the Infection Biology and Molecular Virology laboratories has identified and characterized Schlafen…
Customizing T cell-based immunotherapies using new ‘SNAPtag’ technology
Universal adaptor SNAP-CAR and SNAP-synNotch receptor function. a A benzylguanine motif (BG) is chemically conjugated to an antibody using a benzylguanine NHS ester. The BG-antibody conjugate then covalently binds to…
