Mapping the development of infection-fighting immune cells

Cytotoxic T cell (purple) deciding whether to become a memory cell (blue) or effector cell (pink) subtype. The cBAF complex (green) and Arid1a subunit open the doors for both cell…

Immune cell movement worse in older females, mice study finds

Myeloid immune cells alongside red blood cells in an electron micrograph of human blood. Credit: National Cancer Institute According to a new study, older female mice had more immune cells entering…

Pumping the brakes on autoimmune disease

This visualization shows BTLA being recognized by the antibody LY3361237. Credit: Carl Ware/Sanford Burnham Prebys Researchers at Sanford Burnham Prebys, collaborating with scientists from Eli Lilly and Company, have revealed…

More depressed patients than previously estimated could have increased activation of their immune system

Credit: Unsplash/CC0 Public Domain New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London has used an assessment of gene expression involved in the immune…

One step closer to eliminating latency, the real challenge in combating HIV

Graphical abstract of Shclafen 12 activity. Credit: Pompeu Fabra University An international study led by MELIS-UPF researchers from the Infection Biology and Molecular Virology laboratories has identified and characterized Schlafen…

Customizing T cell-based immunotherapies using new ‘SNAPtag’ technology

Universal adaptor SNAP-CAR and SNAP-synNotch receptor function. a A benzylguanine motif (BG) is chemically conjugated to an antibody using a benzylguanine NHS ester. The BG-antibody conjugate then covalently binds to…

Domestic abuse exposure linked to increased levels of asthma and other atopic diseases

Credit: Pixabay/CC0 Public Domain Women who have suffered domestic abuse may have a higher risk of developing atopic diseases including asthma, new research has found. Published today in the Journal…

How the microbiome affects the immune system

Credit: Pixabay/CC0 Public Domain The building blocks of life-long health are the subject of a cutting-edge review examining how a newborn’s lung microbiome affects the immune system for years to…

Discovery could improve survival of bladder cancer patients

Credit: Unsplash/CC0 Public Domain In a discovery that could improve the survival of bladder cancer patients, Northwestern Medicine scientists have developed a biomarker signature test to predict which tumors will…

Two studies analyze natural killer cells as they tackle the worst form of malaria

Antibody-mediated NK cell activity in children: (A) Merozoite opsonizing antibodies from Junju adults (n=40) induced a significantly higher proportion of ab-NK cells degranulation compared to Junju children (n=293). Hyperimmune (PHIS)…