A microarray-based high-throughput in situ tagged immunoprecipitation sequencing technology for diffuse midline glioma

Graphical abstract. Credit: hLife (2024). DOI: 10.1016/j.hlife.2024.07.004 Diffuse midline glioma (DMG) is a highly aggressive and fatal pediatric high-grade glioma that primarily affects critical regions of the central nervous system,…

Researchers identify role of Parkinson’s-related protein in cancer and T cell activation

Credit: Journal of Clinical Investigation (2024). DOI: 10.1172/JCI180983 A team from the Wistar Institute has demonstrated the role of Parkin—a protein implicated in Parkinson’s disease—in the body’s innate immune response…

Long-term metastatic melanoma survival dramatically improves on immunotherapy, clinical trial finds

Credit: CC0 Public Domain Long-term data from a landmark international trial show about half of patients with metastatic melanoma treated with a combination of immune checkpoint inhibitors survive cancer-free for…

Combination therapy reduced agitated delirium in patients with advanced cancers

Credit: Unsplash/CC0 Public Domain Treatment with a combination of haloperidol and lorazepam reduced symptoms of agitated delirium, a common end-of-life condition for patients with advanced cancers, compared with haloperidol alone,…

Sex matters in how, when, and where melanomas develop

Fitted temporal trend of invasive cutaneous melanoma incidence (1982- 2018) for males vs. females from three populations (Queensland, US Whites, Scotland), by body site. Credit: Journal of Investigative Dermatology (2024).…

Study identifies five key factors that predict response of cancer patients to immunotherapy

Credit: Unsplash/CC0 Public Domain A team of researchers at IRB Barcelona has identified five independent factors that predict cancer patients’ response to checkpoint inhibitors (CPIs). The study, which has been…

Protein NSD2 found to drive early prostate cancer development

Prostate cancer cells. Credit: NIH Image Gallery Researchers at the University of Michigan Health Rogel Cancer Center have uncovered a key reason that a typically normal protein goes awry and…

PanCan nodule management protocol found more effective than LungRADSv1.1 method

Credit: Pixabay/CC0 Public Domain New data presented today reveals that the PanCan nodule management protocol demonstrates superior performance in triaging lung cancer screening participants compared to the LungRADSv1.1 approach. Specifically,…

Does intermittent fasting increase or decrease risk of cancer?

Credit: Unsplash/CC0 Public Domain Research over the years has suggested intermittent fasting has the potential to improve our health and reduce the likelihood of developing cancer. So what should we…

Bioengineers develop lotus leaf-inspired system for cancer research

Alexandria Carter. Credit: Gustavo Raskosky The lotus leaf is a pioneer of self-cleaning, water-repellant engineering. Water droplets all but hover on its surface, whose unique texture traps air in its…