Disruption of Striatal D2 Receptor Neurons Drives ADHD and Impulsivity

Summary: Researchers have demonstrated that deleting the membrane-fusion protein NSF specifically from dopamine D2 receptor (D2R)-expressing neurons leads to striatal shrinkage, severe dopamine depletion, and classic ADHD-like hyperactivity and impulsivity…

Study Reveals Dopamine’s Limited Role in Rapid Neural Activity

Summary: A recent study has found that dopamine signals have a minimal impact on rapid neural activity in the striatum, challenging existing theories about dopamine’s role in brain signaling. Using…

The Brain’s Support Cells May Play a Key Role in OCD

Summary: A newly discovered cellular mechanism that involves astrocytes, as well as neurons, appears to be involved in repetitive behaviors and OCD. Source: UCLA A type of cell usually characterized…