How Depression Alters Stress, Health, and Lifespan

Summary: Depression disrupts the body’s stress systems, causing physical health risks like heart disease, diabetes, and stroke, and reducing life expectancy by 7-10 years. The condition triggers brain structure changes,…

Targeting Liver X Receptor Beta for Depression Treatment

Summary: A recent review highlights the potential of liver X receptor beta (LXRβ) as a target for treating depression and anxiety. Known for regulating cholesterol, LXRβ is emerging as a…

Neurodevelopmental Disruptions Behind Schizophrenia Cognitive Deficits

Summary: A recent review of genetic and population studies reveals that premorbid cognitive deficits in schizophrenia, such as lower IQ, are largely due to neurodevelopmental disruptions rather than inherited genetic…

RNA Therapy Improves Memory and Reduces Anxiety

Summary: An RNA-based therapy, COG-201, can enhance memory and reduce anxiety in animal models by targeting the serotonin 5-HT2A receptor. Scientists found that decreasing this receptor’s expression led to improved…