Why Psychedelics Make Everything Feel Deeply Connected

Summary: Researchers introduce “apical hypercontextualisation”—a bottom-up neurobiological mechanism explaining how psychedelics (psilocybin, LSD, DMT, mescaline) transform perception and cognition. Moving beyond macro-scale whole-brain neuroimaging, the framework focuses on the cellular…

Early Stress Heightens Adult Anxiety

Summary: Researchers uncovered a fundamental epigenetic mechanism explaining how early-life adversity permanently alters the brain’s stress response networks. The study identified that childhood trauma increases levels of the enzyme SETD7…

How Overconfidence and Loss Aversion Co-Evolved

Summary: Researchers propose an evolutionary resolution to why human overconfidence persists despite causing costly decision-making errors. The study argues that overconfidence functions analogously to a peacock’s tail: a costly evolutionary…

As fires burn and temperatures soar, it’s time to imagine a world beyond GDP

Steven Stone is acting director of the United Nations Environment Programme’s Office of Science In 1934, American economist Simon Kuznets presented a paper to Congress advocating for a new way…

The typical gig worker is changing – and struggling more than ever to make ends meet

The next time you call an Uber ride or order food delivery with an app, there’s a good chance that the gig worker you meet is getting government benefits. In…

DIY peptide injections are risky, and people may make serious mistakes when administering them

DIY peptide injections, which promise to boost everything from weight loss and muscle-building to longevity and sexual health, are a high-risk wellness fad that keeps on growing. Health experts have…

Selling sickness: How RFK Jr. and wellness influence grifters turned “inflammation” into a racket

While some health advocates believe raising awareness about inflammation is important, the MAHA movement has twisted it, devaluing the struggles chronically ill people with inflammatory disorders actually face. … This inflammation…

Why you don’t need a perfectly clear sky to enjoy the total solar eclipse on Aug. 12

Are you ready for the eclipse? Whether you’re bound for the path of totality or set to see a partial eclipse from Europe, Canada or the northeast U.S. on Wednesday,…

Rare sculptures of Asklepios and Telesphoros unearthed in Turkey

Archaeologists excavating the ancient city of Aspendos in southern Turkey have uncovered an 1,800-year-old marble statue group depicting Asklepios, the Greek god of medicine, alongside his son Telesphoros, offering new…

Peripheral Blood Cells Replenish Aging Human Microglia

Summary: Researchers revealed that aging leads to a massive, previously unrecognized migration of peripheral blood stem cell-derived immune cells into the human brain. The team dismantled the long-held dogma that…