Summary: Schizophrenia and related psychotic disorders are often preceded by “silent” brain vulnerabilities long before symptoms like hallucinations emerge. A groundbreaking study has identified a potential culprit: the glymphatic system,…
Category: hippocampus
Cocaine Addiction is a Biological Rewiring, Not a Choice
Summary: Relapse isn’t a failure of willpower—it’s a biological “rewiring” of the brain. A new study reveals how chronic cocaine use hijacks the connection between the brain’s reward center and…
Hippocampus Predicts Rewards by Reorganizing Memories
Summary: A new preclinical study reveals that the hippocampus does more than just store memories; it actively reorganizes them to predict future rewards. By tracking brain activity over several weeks,…
Stress-Like Behaviors Traced to a Single ATP Circuit in the Brain
Summary: New research reveals that reduced ATP signaling in the hippocampus plays a causal role in both depression- and anxiety-like behaviors. In stressed male mice, ATP levels and the ATP-releasing…
Do You Get Déjà Vu? Memory Glitches Make Time Feel Repeated
Summary: Déjà vu—the eerie feeling that a new moment has happened before—has puzzled scientists and philosophers for centuries. Neuroscientists now believe it’s a normal brain glitch tied to how memory…
Environment and Hippocampal Size Impact Depression in Youth
Summary: Challenging social environments and the size of the left hippocampus in children aged 9-11 contribute to an increased risk of depression. Researchers found that children with larger hippocampal volumes…
Glutamate Imbalance Impairs Hippocampus, Leading to Psychosis
Summary: A new study has found that people with a genetic risk for psychosis have an imbalance of glutamate and GABA neurotransmitters in their brains, specifically in the hippocampus. This…
