Study Challenges Longstanding Beliefs About Action of Antipsychotic Medications

Summary: Researchers uncovered a pivotal detail that could revolutionize schizophrenia treatment. Contrary to longstanding belief, antipsychotic drugs that mitigate overactive dopamine, a hallmark of schizophrenia, interact primarily with a different…

Schizophrenia Linked to Non-Inherited Genetic Mutations

Summary: Researchers found a link between schizophrenia and somatic copy-number variants, mutations occurring post-inheritance. The study scrutinized genotype-marker data from over 20,000 blood samples, identifying two genes, NRXN1 and ABCB11,…

Shaping Young Minds: Neurodevelopment Interventions for Psychiatric Disorders

Summary: Researchers explored potential treatments for neuropsychiatric disorders like schizophrenia and autism that act during critical windows of brain development. They specifically targeted underperforming dopamine neurons, which connect to the…

Unexpected Role of Immune Autoantibodies in Schizophrenia

Summary: A study reveals a connection between schizophrenia and autoimmune reactions. The researchers identified autoantibodies against the synaptic protein neurexin 1α in about 2% of patients with schizophrenia. These autoantibodies,…

Understanding Delusions of Control: How Schizophrenia Alters Perception of Action

Summary: A new study sheds light on the phenomenon of ‘delusions of control’, often experienced by schizophrenia patients. This condition, marked by the belief that one’s actions are controlled by…

Schizophrenia Risk Genes: Placenta’s Role May Outweigh Brain’s

Summary: In a paradigm shift, researchers found over 100 genes associated with schizophrenia risk operate primarily through their role in the placenta, rather than the developing brain. The research emphasizes…