After receiving an experimental treatment to stop the body from attacking itself, five people no longer have any symptoms of lupus.
That treatment, called CAR-T cell therapy, seems to have reset the patients’ immune systems, sending their autoimmune disease into remission, researchers report September 15 in Nature Medicine. It’s not yet clear how long the relief will last or whether the therapy will work for all patients.
Even so, the results could be “revolutionary,” says immunologist Linrong Lu of the Shanghai Immune Therapy Institute at the Shanghai Jiao Tong University School of Medicine, who was not involved in the study. CAR-T cell therapy has been used for various types of cancer, but it’s still in testing for autoimmune diseases (SN: 2/2/22).
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