Key Questions Answered Q: What did researchers discover about the serotonin 5-HT1A receptor?A: They mapped how it activates different brain signaling pathways, offering insight into how mood and emotion are…
Tag: Antidepressants
How FDA panelists casting doubt on antidepressant use during pregnancy could lead to devastating outcomes for mothers
At a meeting held by the Food and Drug Administration on July 21, 2025, a panel convened by the agency cast doubt on the safety of antidepressant medications called selective…
How mothers supporting mothers can help fill the health care worker shortage gap and other barriers to care
For generations, women have relied on informal networks of friends, family and neighbors to navigate the complexities of birth and motherhood. Today, research is finally catching up to what generations…
Boosting Ketamine’s Antidepressant Effects to Last Two Months
Summary: Ketamine is a fast-acting antidepressant that can relieve symptoms of major depressive disorder (MDD) within hours, even in treatment-resistant cases. However, its effects typically last only a week, and…
Can Brain Scans Tell Which Antidepressant Will Work for You?
Summary: A new study shows that brain connectivity patterns, especially in the dorsal anterior cingulate cortex, can help predict how patients with major depressive disorder (MDD) will respond to antidepressants.…
How Psilocybin Lifts Mood Without the Hallucinogenic Trip
Summary: Researchers have uncovered two key brain mechanisms—specific neurons and a serotonin receptor—that help explain how psilocybin produces long-lasting antidepressant effects. Their study identified pyramidal tract neurons in the medial…
SSRIs May Speed Up Cognitive Decline
Summary: A new study based on data from 18,740 dementia patients suggests that antidepressants may accelerate cognitive decline. Researchers found that patients taking antidepressants, particularly SSRIs like escitalopram, citalopram, and…
How Ketamine Binds to Brain Receptors to Alter Mood
Summary: New research sheds light on how ketamine affects the brain by targeting a specific NMDA receptor subtype, GluN1-2B-2D. Scientists used electron cryo-microscopy to capture how ketamine binds to this…
Prozac Shows Promise in Fighting Infections & Sepsis
Summary: New research suggests that fluoxetine, commonly used as an antidepressant, may also help protect against infections and sepsis. Scientists found that the drug has antimicrobial properties and helps regulate…
