Twin Dynamics: How Developmental Differences Shape Dominance Roles

Summary: A new study reveals that developmental differences strongly influence dominance roles in twin relationships, with typically developing twins perceived as dominant over their nontypically developing siblings. This dominance imbalance…

Collaborative seeks to change children’s lives through genetics

Overview of participants and data included in the CRDC. Credit: npj Genomic Medicine (2024). DOI: 10.1038/s41525-024-00441-9 A 14-year-old girl was having back pain after a car accident and visited an…

Genetic Mechanism Links Emotional Experiences to Behavior Changes

Summary: Researchers have identified a genetic mechanism that regulates behavioral adaptations to emotional experiences by forming R-loops, unique RNA:DNA structures that activate target genes. The study focused on NPAS4, a…

RNA:DNA ‘sandwich’ plays key role in behavioral adaptations arising from emotional experiences, research reveals

Medical University of South Carolina neuroscience researchers who are co-authors on the December 13 Science paper. From left to right: Rose-Marie Akiki, Dr. Christopehr Cowan, and Dr. Makoto Taniguchi. Credit:…

Base editing, a new form of gene therapy, leaves patient feeling ‘more than fine’

Credit: National Institutes of Health Though he doesn’t remember it, Branden Baptiste had his first sickle cell crisis at age 2. Through elementary school, he was in and out of…

New Appetite Regulating Neurons Discovered

Summary: Researchers have identified a previously unknown population of neurons in the hypothalamus that play a critical role in regulating appetite. These neurons express both leptin receptors and the BNC2…

Depression Genes in Women Linked to Higher Heart Disease Risk

Summary: A new study analyzing genetic data from over 300,000 people revealed that women with a high genetic risk for depression also face a higher likelihood of developing heart disease,…

Evaluating long-term survival and cardiac efficacy of a gene therapy for Duchenne muscular dystrophy

Fibrotic remodeling in skeletal muscle and heart of DMDMDX rats and impact of delandistrogene moxeparvovec treatment. A recent study published in the journal Human Gene Therapy evaluated the long-term survival…

Leaded Gas Exposure Linked to Mental Illness

Summary: A new study estimates that childhood lead exposure, peaking between 1960 and 1990 due to leaded gasoline, caused 151 million excess cases of mental illness by 2015. Researchers linked…

Family History of Mental Illness Increases Aggression Risk in CTE

Summary: A new study reveals that individuals with chronic traumatic encephalopathy (CTE) and a family history of mental illness have a heightened risk of aggression during adulthood, particularly between ages…