1 gene, 1 disease no more – acknowledging the full complexity of genetics could improve and personalize medicine

Genetic inheritance may sound straightforward: One gene causes one trait or a specific illness. When doctors use genetics, it’s usually to try to identify a disease-causing gene to help guide…

Dietary RNA Molecules May Hold the Key to Slowing Cellular Aging

Summary: Living longer doesn’t always mean living healthier, and researchers are exploring how diet can extend healthspan. A study in worms shows that specific dietary RNA molecules protect cells from…

Early Clues to Autism and Schizophrenia Risk Found in DNA

Summary: Researchers have built a detailed map of DNA methylation changes in nearly 1,000 human brains from six weeks after conception to old age. The work reveals dramatic epigenetic shifts…

AI Reveals Bitter Taste Receptors’ Hidden Role in Gut-Brain Health

Summary: Researchers used AlphaFold3, the latest AI-based protein modeling system, to predict the structures of all 25 known human bitter taste receptors (T2Rs). Compared with AlphaFold2, AF3 consistently generated more…

How Neurons Pick Just One Scent Receptor

Summary: Researchers studying clonal raider ants have uncovered how each sensory neuron manages to express just one odorant receptor gene from a library of hundreds. Unlike fruit flies or mammals,…

Evolution of Human Brain May Explain High Autism Rates

Summary: A new study suggests that autism may be linked to the rapid evolution of brain cell types unique to humans. Researchers found that outer-layer neurons in the human brain…

Brain Cells Behind Depression Identified

Summary: Researchers analyzing post-mortem brain tissue found two cell types altered in people with depression: excitatory neurons that regulate mood and stress, and microglia that manage inflammation. The findings highlight…

Eight New Genes Linked to Schizophrenia Revealed

Summary: The largest exome-sequencing study of schizophrenia to date has uncovered eight new genes tied to the disorder. Two genes, STAG1 and ZNF136, were strongly implicated, while six others showed…

Bipolar Mood Shifts Linked to Insulin Signaling in the Pancreas

Summary: A new study uncovers a pancreas–hippocampus feedback loop that may help explain mood swings in bipolar disorder. Using patient-derived pancreatic islets, researchers found reduced insulin secretion linked to elevated…

First “Microwave Brain” Chip Merges Ultrafast Data and Wireless Signals

Summary: Researchers have built the first “microwave brain” chip capable of processing both ultrafast data and wireless communication signals at once. By harnessing analog, nonlinear microwave physics instead of conventional…