Summary: War exposure in Syrian refugee children triggered unique DNA methylation changes, marking genes involved in brain development and stress responses. These epigenetic changes suggest potential long-term effects on health…
Tag: Genetics
Large-scale genetic study identifies 14 genes linked to neuroticism
Study overview. Credit: Nature Human Behaviour (2024). DOI: 10.1038/s41562-024-02045-w Neuroticism is a key personality trait described by well-established psychological theories, associated with a tendency towards emotional instability and negative emotions.…
New Gene-Editing Tool Targets Mutations with Unmatched Precision
Summary: A breakthrough tool called Helicase-Assisted Continuous Editing (HACE) allows scientists to create precise genetic mutations in specific genes without affecting the rest of the genome. By combining helicase enzymes…
Mapping Protein Changes Across Aging
Summary: Researchers have developed the Mouse Aging Proteomic Atlas, a comprehensive database detailing protein changes in major tissues as mice age. By analyzing proteomes and transcriptomes across tissues like the…
Huntington’s Gene Enhances Early Brain Growth and Intelligence
Summary: A study reveals that the genetic mutation causing Huntington’s disease (HD) enhances brain development and intelligence in early life, but leads to degeneration in adulthood. Children with the HD…
Glial Cells May Influence Depression and Schizophrenia
Summary: New research highlights neuroglia (or glia cells) as critical players in mental health, potentially influencing conditions like depression and schizophrenia. Glia cells, long considered “support cells” in the brain,…
How higher brain care score can improve brain health regardless of genetic risk
Credit: RDNE Stock project from Pexels A study, published in the journal Neurology has explored whether healthy lifestyle choices, measured by a Brain Care Score (BCS), can lower the risk…
Stem cells can tailor their role in gene therapy based on the underlying disease, study suggests
Credit: CC0 Public Domain RCCS San Raffaele Scientific Institute in Milan researchers have discovered that hematopoietic stem cells (HSCs) adapt their lineage commitment during gene therapy based on the underlying…
Key Biochemical Trigger of Huntington’s Disease Progression Identified
Summary: Researchers have identified a crucial biochemical mechanism that could allow Huntington’s disease to be studied before symptoms appear, offering hope for early intervention. The team found that disrupted dopamine…
Researchers identify deletions in long noncoding RNA that lead to severe neurodevelopmental disorder
Credit: Unsplash/CC0 Public Domain Broad Institute-led research has revealed that deletions in the CHASERR gene cause a distinct neurodevelopmental disorder resulting in severe encephalopathy, cortical atrophy, and cerebral hypomyelination. Developmental…
