How do rare genetic variants affect health? AI provides more accurate predictions

Credit: Pixabay/CC0 Public Domain Whether we are predisposed to particular diseases depends to a large extent on the countless variants in our genome. However, particularly in the case of genetic…

100+ Genes Linked to Anxiety Disorders Identified

Summary: A large-scale genetic study involving over 1 million participants has uncovered more than 100 genes associated with anxiety. Researchers found that these genes contribute to the development of anxiety…

Food fussiness a largely genetic trait from toddlerhood to adolescence, study suggests

Credit: Pixabay/CC0 Public Domain Fussy eating is mainly influenced by genes and is a stable trait lasting from toddlerhood to early adolescence, finds a new study led by researchers from…

New insights into genetic and environmental interplay

Credit: Pixabay/CC0 Public Domain In the complex landscape of mental health research, a new viewpoint offers a critical examination of how genes and environment conspire to influence schizophrenia risk. Published…

Gene Therapy Offers Hope for Glaucoma and AMD

Summary: A newly developed gene therapy shows great potential for treating glaucoma, a condition that can lead to vision loss. The therapy protects retinal ganglion cells, essential for vision, and…

Protein NSD2 found to drive early prostate cancer development

Prostate cancer cells. Credit: NIH Image Gallery Researchers at the University of Michigan Health Rogel Cancer Center have uncovered a key reason that a typically normal protein goes awry and…

Role of Serotonin Release in Depression Uncovered

Summary: Researchers developed a highly selective fluorescent probe to image serotonin in cells and animal models, shedding light on its role in depression. The study revealed that while serotonin levels…

Neurodevelopmental Disruptions Behind Schizophrenia Cognitive Deficits

Summary: A recent review of genetic and population studies reveals that premorbid cognitive deficits in schizophrenia, such as lower IQ, are largely due to neurodevelopmental disruptions rather than inherited genetic…

RNA Therapy Improves Memory and Reduces Anxiety

Summary: An RNA-based therapy, COG-201, can enhance memory and reduce anxiety in animal models by targeting the serotonin 5-HT2A receptor. Scientists found that decreasing this receptor’s expression led to improved…

Schizophrenia Linked to Disrupted Synaptic Plasticity

Summary: Researchers have identified a mechanism that impairs synaptic plasticity in individuals with schizophrenia, revealing the role of three key proteins. Using computational modeling, the team explored how genetic alterations…