TIAN induces antiallodynic effects more rapidly than DMI. Credit: Neuropsychopharmacology (2023). DOI: 10.1038/s41386-023-01645-w Neuropathic pain is a debilitating condition estimated to affect as much as 10% of the global population.…
Tag: Medications
New opioid use raises death risk 11-fold in those with dementia
Older adults who begin using opioid painkillers after a dementia diagnosis have a significantly greater risk of death—about 11-fold within the first two weeks, according to new research. The risk…
What they are, how they work, and why you need to know about them
Credit: Pixabay/CC0 Public Domain Last month, nearly 12,000 people gathered in Denver to talk about magic mushrooms (psilocybin), ecstasy (MDMA), ibogaine and ayahuasca, and to discuss the latest scientific research…
Anti-inflammatory drugs did not speed COVID-19 recovery but prevented deaths, national study finds
Two anti-inflammatory drugs, abatacept and infliximab, reduced deaths among patients hospitalized with severe COVID-19, according to a national study led by Washington University School of Medicine in St. Louis. William…
Leveraging phosphorothioate backbone modification to optimize aptamer-drug conjugates for therapeutic agent delivery
a) Cell uptake efficiency of Cy5-XQ-2d, Cy5-S-XQ-2d, Cy5-MFSX, and Cy5-MFC by PL45 cells. b) The ratio of Geometric Mean Fluorescence Intensity to Cy5-MFC for Cy5-XQ-2d, Cy5-S-XQ-2d, or Cy5-MFSX uptake by…
Australia is the first country to let patients with depression or PTSD be prescribed psychedelics
Artwork on display is seen at the Psychedelic Science conference in the Colorado Convention Center Wednesday, June 21, 2023, in Denver. Australia is the first country to allow psychiatrists to…
Team introduces new approach in cancer therapy with innovative mechanism-of-action for ferroptosis induction
FSP1 condensates in green induced by icFSP1 surrounding a blue nucleus. Credit: Toshitaka Nakamura A team of researchers led by Dr. Marcus Conrad from Helmholtz Munich has discovered a novel…
New drugs line up to challenge Ozempic, Wegovy for weight loss
After drugmaker Novo Nordisk tweaked its diabetes drug Ozempic into Wegovy—a formulation expressly designed to help users shed pounds—sales of both drugs skyrocketed. Other pharmaceutical giants took notice, and over…
Guidelines to help clinicians on safer opioid deprescribing
Credit: Unsplash/CC0 Public Domain Australian and international experts have released 11 recommendations on when, how, and in what situation it may be appropriate for clinicians to reduce opioid use, by…
Study reports drug that significantly reduces bacteria’s ability to develop antibiotic resistance
Credit: Pixabay/CC0 Public Domain A team of researchers at Baylor College of Medicine is gaining ground in their search for solutions to the global problem of bacterial antibiotic resistance, which…
