Optimism Boosted by Psilocybin, Hinting at Depression Relief

Summary: Researchers have discovered that psilocybin, a psychedelic compound in magic mushrooms, increases optimism and motivation in rats, suggesting potential therapeutic benefits for treating depression. Using computational modeling, scientists observed…

High-Dose Psilocybin Shows Potential as an Antidepressant Treatment

Summary: A meta-analysis suggests that high doses of psilocybin may alleviate depressive symptoms similarly to the SSRI drug escitalopram. While the effect size was small, psilocybin outperformed placebo in clinical…

Psilocybin legislation is helping psychedelic drugs make a comeback – a drug researcher explains the challenges they face

An operations manager finds relief from her depression with the help of psilocybin, the primary psychoactive component of “magic mushrooms.” A veteran conquers his post-traumatic stress disorder through therapy using…

Mind-Bending: Psilocybin Reshapes Brain Networks for Weeks

Summary: A new study reveals that psilocybin, the active compound in magic mushrooms, temporarily disrupts brain networks involved in introspective thinking, like daydreaming and memory. These changes persist for weeks,…

Calls to US poison centers spiked after ‘magic mushrooms’ were decriminalized

Calls to poison control centers spiked across the U.S. for adolescents and young adults exposed to the hallucinogen psilocybin, according to our analysis of data from 55 U.S. poison centers…

How cannabis and psilocybin might help some of the 50 million Americans who are experiencing chronic pain

The U.S. Drug Enforcement Agency announced in late April 2024 that it plans to ease federal restrictions on cannabis, reclassifying it from a Schedule I drug to the less restricted…

Psilocybin Microdosing Promising for Mental Health Disorders

Summary: Researchers delve into the therapeutic potential of psilocybin microdosing, exploring its influence on stress resilience and compulsive behaviors in rats. While high-dose psilocybin therapy has been scrutinized for psychiatric…

Psychedelics may better treat depression and anxiety symptoms than prescription antidepressants for patients with advanced cancer

In people with advanced cancer, psychedelic drugs like psilocybin, LSD and MDMA may significantly reduce the severity of depression and anxiety symptoms. Roughly 10% of patients with cancer experience anxiety,…