Summary: Researchers delivered the world’s first in vivo (in a living organism) evidence of widespread muscarinic acetylcholine M1 receptor deficits in schizophrenia. Utilizing a pioneering, highly selective PET radiotracer, the…
Tag: Schizophrenia
Brain Scans Reveal a Network Origin Point for Schizophrenia
Summary: A new study utilized specialized Positron Emission Tomography (PET) imaging to measure synaptic connections in the living human brain. Evaluating one of the largest clinical cohorts of its kind…
When Hearing Voices Functions as a Coping Mechanism
Summary: Researchers launched a pioneering set of clinical resources, including a practical guide and a short documentary film. The project proves that hearing voices can often function as an adaptive,…
Ketogenic Diet Eases Schizophrenia and Bipolar Symptoms
Summary: Researchers demonstrated that a ketogenic diet, which shifts the body away from glucose and toward fat-derived ketones for fuel, induces rapid metabolic improvements and alleviates persistent psychiatric symptoms. By…
Preconception Maternal Trauma Doubles Schizophrenia Risk
Summary: A new study demonstrated that women who endured Nazi persecution as young girls passed a significantly elevated risk of psychiatric illness to their children born decades after World War…
Network Mapping Uncovers 641 Hidden Schizophrenia Risk Genes
Summary: Researchers have revolutionized psychiatric genomics by identifying 641 previously unrecognized genes associated with schizophrenia. The study analyzed genetic datasets from over 102,000 individuals alongside postmortem brain tissue samples spanning…
Combining Cannabis and Tobacco Triples Psychosis Risk
Summary: A multi-site study reveals that combining cannabis and tobacco, a trend known as “co-use”, significantly increases the long-term risk of developing full psychotic disorders like schizophrenia. The study tracked…
Genetic Pathways Link Cannabis Use to Psychosis Risk
Summary: New research provides a breakthrough in understanding the biological mechanisms linking Cannabis Use Disorder (CUD) and psychosis. By conducting a large-scale genetic meta-analysis, researchers identified over 500 genetic loci…
Map of Brain Histamine System Links Molecule to ADHD and Depression
Summary: Researchers developed the first multiscale map of the brain’s histamine system, spanning from genetics to behavior. While histamine is famously linked to allergies, this study highlights its critical, often-overlooked…
ADHD Medication May Shield Against Psychosis
Summary: A major study has found that treating ADHD with stimulant medication during childhood may actually lower the long-term risk of developing serious psychotic disorders, such as schizophrenia. The research…
