Summary: Researchers have identified a rare type of brain cell whose overactivity may contribute to schizophrenia-like symptoms, such as cognitive deficits and disrupted sleep. When scientists reduced the activity of…
Tag: Schizophrenia
Hearing Voices May Stem from the Brain Misreading Its Own Inner Speech
Summary: A new study reveals that auditory hallucinations in schizophrenia may arise when the brain fails to recognize its own inner voice as self-generated. Normally, the brain predicts the sound…
Early Clues to Autism and Schizophrenia Risk Found in DNA
Summary: Researchers have built a detailed map of DNA methylation changes in nearly 1,000 human brains from six weeks after conception to old age. The work reveals dramatic epigenetic shifts…
Mini Brains Expose Neural Signatures of Schizophrenia and Bipolar
Summary: For the first time, lab-grown mini brains have revealed how neurons misfire in schizophrenia and bipolar disorder. Using machine learning to analyze electrical activity, researchers identified distinct firing patterns…
Sex Shapes the Course of Bipolar Disorder and Schizophrenia
Summary: A large multicenter study has revealed that sex influences the course and characteristics of schizophrenia and bipolar disorder. Women with schizophrenia tended to begin treatment later, while men with…
High-THC Cannabis Linked to Psychosis and Addiction
Summary: A systematic review of nearly 100 studies found that high-THC cannabis products are linked to negative mental health outcomes, particularly psychosis, schizophrenia, and cannabis use disorder. While some therapeutic…
Eight New Genes Linked to Schizophrenia Revealed
Summary: The largest exome-sequencing study of schizophrenia to date has uncovered eight new genes tied to the disorder. Two genes, STAG1 and ZNF136, were strongly implicated, while six others showed…
Could Mental Illness Begin Before You’re Born?
Key Questions Answered: Q: When do genes linked to mental illness start affecting the brain?A: Many genes associated with neuropsychiatric and neurodegenerative diseases are active during the earliest stages of…
Most Mental Illnesses Arise Without Family History
Summary: A massive Danish study shows that most mental illnesses—like schizophrenia, bipolar disorder, and depression—occur in people with no close family history of the condition. Analyzing data from over 3…
