Abuse Survivors Show Unique Injury Signatures Tied to Suicide Risk

Summary: A new study finds that victims of intimate partner violence who also experience suicidal thoughts or behaviors show distinct and severe injury patterns on medical imaging. These patients were…

Genetics Point to a New Type of Suicide Risk

Summary: New research shows that many people who die by suicide without prior suicidal thoughts or behaviors are not simply “missed cases”—they may have an entirely different underlying risk profile.…

Stress-Like Behaviors Traced to a Single ATP Circuit in the Brain

Summary: New research reveals that reduced ATP signaling in the hippocampus plays a causal role in both depression- and anxiety-like behaviors. In stressed male mice, ATP levels and the ATP-releasing…

Shocking Disparities: Women Face Higher Risk of ECT

Summary: A large international survey of 858 electroconvulsive therapy recipients found that women are twice as likely as men to receive ECT and experience more adverse effects. Women reported higher…

Genetic Roots of Depression Reveal Strong Suicide Risk Signals

Summary: New research shows that depression beginning before age 25 has a much stronger hereditary component than depression that emerges later in life. By analyzing genetic data from over 150,000…

Common Antidepressant Eases Core Symptoms Within Two Weeks

Summary: A new analysis of the PANDA clinical trial reveals that sertraline, one of the most prescribed antidepressants, improves key emotional symptoms of depression—such as sadness, self-loathing, and suicidal thoughts—within…

Toddler Gut Bacteria Linked to Childhood Anxiety and Depression

Summary: A new study suggests that a child’s gut microbiome at age 2 may influence their emotional health years later. Researchers found that higher levels of bacteria from the Clostridiales…

Reelin Shows Promise for Healing Both Gut and Depression

Summary: A new study reveals that the protein Reelin may hold the key to treating both “leaky gut” and major depressive disorder. Chronic stress lowers Reelin levels in the gut,…

Psilocybin Rewire Brain Circuits Tied to Pain and Mood

Summary: New research shows that psilocybin, the active compound in psychedelic mushrooms, can reduce both chronic pain and pain-related depression by modulating brain circuits rather than acting at the site…

Sugary Drinks Linked to Depression Through Gut Microbiome

Summary: A new study shows that sugary drinks don’t just affect physical health—they may also raise the risk of depression in women by disrupting the gut microbiome. Researchers found that…