Abstract Macroautophagy is a catabolic process that coordinates with lysosomes to degrade aggregation-prone proteins and damaged organelles. Loss of macroautophagy preferentially affects neuron viability and is associated with age-related neurodegeneration.…
Category: Neuroscience
A Novel CCK Receptor GPR173 Mediates Potentiation of GABAergic Inhibition
Introduction Cholecystokinin (CCK), the most abundant and widely distributed neuropeptide in the CNS (Crawley and Corwin, 1994), colocalizes with glutamate (Morino et al., 1994), GABA (Somogyi et al., 1984; Markram…
Neural Substrates of Body Ownership and Agency during Voluntary Movement
Abstract Body ownership and the sense of agency are two central aspects of bodily self-consciousness. While multiple neuroimaging studies have investigated the neural correlates of body ownership and agency separately,…
Severely Attenuated Visual Feedback Processing in Children on the Autism Spectrum
Introduction Individuals on the autism spectrum demonstrate atypicality in sensory processing across multiple domains. Given that efficient integration of basic sensory information forms a foundation for more complex cognition and…
Hindbrain Adenosine 5-Triphosphate (ATP)-Purinergic Signaling Triggers LH Surge and Ovulation via Activation of AVPV Kisspeptin Neurons in Rats
Abstract Ovulation disorders are a serious problem for humans and livestock. In female rodents, kisspeptin neurons in the anteroventral periventricular nucleus (AVPV) are responsible for generating a luteinizing hormone (LH)…
Enhanced Reactivation of Remapping Place Cells during Aversive Learning
Introduction Episodic memories include details about salient experiences from our past as well as information about the location in which these events occurred (Tulving, 1972). The hippocampus plays a central…
Sensory and Choice Responses in MT Distinct from Motion Encoding
Introduction Primate middle temporal (MT) area plays a critical role in the perception of visual motion. A long line of study has established that MT’s encoding of motion direction is…
Adult mouse brains are teeming with ‘silent synapses’
Learning lots of new information as a baby requires a pool of ready-to-go, immature connections between nerve cells to form memories quickly. Called silent synapses, these connections are inactive until…
Rats can bop their heads to the beat
Humans aren’t the only animals known to move to a musical beat. For instance, parrots do it, too. And now rats have been observed bopping their heads in time with…
New brain implants ‘read’ words directly from people’s thoughts
SAN DIEGO — Scientists have devised ways to “read” words directly from brains. Brain implants can translate internal speech into external signals, permitting communication from people with paralysis or other…
