Rendering of interface in the mutant EGFR studied that was shown to be critical for EGFR-driven tumor growth. The K946E mutation shown in red was used by the team to…
Tag: Genetics
Molecular Alterations in Brain Tissue Provide Clues to Suicidal Ideation
Summary: Researchers have identified molecular alterations in the blood and brain tissues of individuals who committed suicide, offering new insights into susceptibility factors and therapeutic targets. The study analyzed genetic,…
Unlocking Synaptic Mysteries: The Role of FAM81A Protein
Summary: Researchers have identified a critical protein, FAM81A, that plays a pivotal role in forming postsynaptic protein agglomerations, essential for synaptic function in the brain. By analyzing 35 previous studies,…
For childhood cancer survivors, inherited genetic factors influence risk of cancers later in life
Credit: Unsplash/CC0 Public Domain Common inherited genetic factors that predict cancer risk in the general population may also predict elevated risk of new cancers among childhood cancer survivors, according to…
Large-scale study explores link between smoking and DNA changes across six racial and ethnic groups
Credit: CC0 Public Domain Smoking changes the way genes are expressed, which later contributes to the development of lung cancer and other smoking-related illnesses. But the link between epigenetics (the…
Uncovering the connections between autism, sensory hypersensitivity
Credit: CC0 Public Domain Supported by a grant, the Auerbach Lab at the Beckman Institute for Advanced Science and Technology will examine how different genes associated with autism spectrum disorders…
Learning and memory problems in Down syndrome linked to alterations in genome’s ‘dark matter’
The activity of Snhg11 (red) pictured in the dentate gyrus region of the hippocampus in mice. Credit: Cesar Sierra/Centro de Regulación Genómica (CRG) Researchers at the Centre for Genomic Regulation…
Genes Play a Key Role in Trust
Summary: Genetic factors account for approximately 33% of the variation in trust levels between individuals, highlighting the heritable nature of this crucial social trait. The research utilized data from twins…
Unlocking Cell Death Secrets: Lipids Key to Ferroptosis Control
Summary: Researchers have made a groundbreaking discovery, identifying a rare lipid as a crucial factor in ferroptosis, a unique form of cell death. This lipid, characterized by its two polyunsaturated…
