Hitching a Ride: mRNA’s Transport System in Brain Cells Revealed

Summary: Researchers made significant advancements in understanding how mRNA is distributed in brain cells. They discovered that a protein complex called FERRY aids Early Endosomes (EEs) to carry mRNAs to…

Unlocking Addiction Risk: Genetic Test Could Shape Future Prevention Strategies

Summary: A new study hints at the potential of utilizing genetic test results to improve addiction prevention and treatment strategies. The study involved 325 college students who were given varying…

Top 5 Neuroscience News Stories of the Week

Summary: This week, research teams from around the globe shared their remarkable findings from the field of neuroscience. Discoveries ranged from unraveling how Botox breaches neurons, to a study finding…

Gene Therapy Reverses Age-Related Hearing Loss

Summary: Researchers successfully demonstrated the efficacy of adeno-associated virus (AAV) vectors in reversing genetic hearing loss in aged animal models. The scientists developed a mature mouse model with a mutation…

Shared Genetics for Cannabis Use and Psychiatric Disorders

Summary: Researchers discovered shared genetic underpinnings for cannabis use and psychiatric disorders like schizophrenia and bipolar disorder. Employing advanced statistical modeling, the study revealed a complex interplay of genetic variants…

A proposed new metric to quantify genetic dissimilarities between an individual and a training population

Illustration of population-level versus individual-level PGS accuracy. a, Discrete labeling of GIA with PCA-based clustering. Each dot represents an individual. The circles represent arbitrary boundaries imposed on the genetic ancestry…

Researchers find link between obesity and blood cancer

Credit: Unsplash/CC0 Public Domain Indiana University School of Medicine researchers studying clonal hematopoiesis of indeterminate potential (CHIP), a blood condition that may increase the risk of blood cancer, discovered that…

Schizophrenia Risk Genes: Placenta’s Role May Outweigh Brain’s

Summary: In a paradigm shift, researchers found over 100 genes associated with schizophrenia risk operate primarily through their role in the placenta, rather than the developing brain. The research emphasizes…

DNA project gives scientists diverse genome for comparison

Credit: CC0 Public Domain For two decades, scientists have been comparing every person’s full set of DNA they study to a template that relies mostly on genetic material from one…

Cellular ‘cruise control’ system safeguards RNA levels in Rett syndrome nerve cells

Cis-acting elements in the 3ʹUTR are highly associated with half-life changes. a Random forest classifier for prediction of mRNA sequence features relevant for half-life fold-change in human NEURTT and in…