Summary: Scientists developed a mouse model that carries a genetic mutation linked to an increased risk of schizophrenia. By studying the Grin2a gene, they found significant changes in gene expression,…
Tag: Genetics
Schizophrenia gene mutation causes many changes in the mouse brain, new study shows
Researchers studied the effects of a schizophrenia gene mutation in different regions of the mouse brain. Credit: Susanna Hamilton, Broad Communications Researchers have identified common and rare gene mutations that…
Genes Behind Depression Could Pave Way for Other Mental Disorders
Summary: Researchers completed the largest-ever genetic study on depression, encompassing 1.3 million genomes. Their findings indicate that individuals with hospital-treated depression have an increased genetic risk for other psychiatric conditions…
Research team completes long-anticipated genome sequencing of Y chromosome
Researchers have filled in the final pieces of the puzzle for mapping a complete Y chromosome in humans. Credit: N. Hanacek/NIST Twenty years ago, when researchers from the Human Genome…
Scientists discover mutations in blood stem cells can exacerbate colon cancer
Compared with normal mice (top), colonoscopies detect more, and larger, tumors in the intestines of mice with clonal hematopoiesis (bottom). Credit: © 2023 Feng et al. Originally published in Journal…
Unlocking Schizophrenia: Mitochondria Dysfunction at the Forefront
Summary: Researchers have identified a pivotal role of impaired mitochondrial function in the development of schizophrenia by examining the genetic risk factor 3q29 deletion syndrome. The genetic condition, known to…
A ‘memory wipe’ for stem cells may be the key to better therapies
Credit: Pixabay/CC0 Public Domain Stem cells are special kinds of cells in our body that can become any other type of cell. They have huge potential for medicine, and trials…
Research identifies gene ‘fingerprint’ for brain aging
Graphical abstract. Credit: Cell (2023). DOI: 10.1016/j.cell.2023.07.027 Most of us who’ve reached middle age have noticed a slowing in memory and cognition, but scientists don’t have a clear picture of…
AI Pinpoints Parkinson’s Subtypes Using Stem Cell Images
Summary: Researchers enabled machine learning to accurately predict Parkinson’s disease subtypes using stem cell images. This breakthrough showcases computer models classifying four Parkinson’s subtypes, with top accuracies reaching 95%. This…
Team identifies 169 genes associated with production of melanin in the skin, hair and eyes
Genetic screen finds previously unidentified loci for human melanogenesis. By exploiting melanin’s light-scattering properties, we conducted a genome-wide screen and uncovered genes regulating melanin content and hence, melanogenesis, in human…
