3-Region Neural Circuit Required for Sleep Memory

Summary: A human intracranial recording study reveals that memory consolidation during sleep depends on precise, coordinated activity among three brain regions: the orbitofrontal cortex, the thalamus, and the hippocampus. The…

Brain Signal Linked to OCD Compulsions Identified

Summary: Researchers have identified a specific pattern of high-frequency brain activity in the anteromedial orbitofrontal cortex (amOFC) that is consistently linked to compulsive behaviors in people with obsessive-compulsive disorder (OCD).…

Brain Cells That Thrive on Uncertainty Help Us Adapt and Learn

Summary: Scientists have discovered a group of brain cells in the orbitofrontal cortex that become more active when outcomes are uncertain, revealing how the brain adapts and learns from unpredictable…