Summary: New research shows that psilocybin, the active compound in psychedelic mushrooms, can reduce both chronic pain and pain-related depression by modulating brain circuits rather than acting at the site…
Tag: psychopharmacology
Psilocybin Worsens Postpartum Depression Symptoms
Summary: New research shows psilocybin, often studied as a treatment for mental health disorders, may worsen symptoms of postpartum depression in mice. Mothers given the drug showed more anxiety, avoidance…
Cannabis Linked to Reduced Insomnia and Anxiety
Summary: A new study suggests cannabis-based medical products may help people with insomnia sleep better over the long term. Across 124 patients followed for up to 18 months, participants consistently…
Fat Molecule May Control How You Feel Emotion
Key Questions Answered Q: What did researchers discover about the serotonin 5-HT1A receptor?A: They mapped how it activates different brain signaling pathways, offering insight into how mood and emotion are…
More Than Serotonin: How Psychedelics Engage the Whole Brain
Summary: Classical psychedelics like LSD, psilocybin, and mescaline are known for activating the 5-HT2A serotonin receptor, but a new study reveals their effects go far beyond. Researchers profiled 41 psychedelics…
Psilocybin Shows Promise as Anti-Aging Therapy
Summary: Psilocybin, the active compound derived from psychedelic mushrooms, significantly delayed cellular aging and extended lifespan in a preclinical study. Researchers observed a 50% increase in the lifespan of human…
Timing of Prozac Treatment Shapes Lasting Mood, Brain Changes
Summary: New research reveals that the developmental timing of fluoxetine (Prozac) treatment profoundly influences long-term mood and brain function. In a rodent model, early postnatal treatment in males led to…
Gut Microbiome May Influence Bipolar Medication Response
Summary: A new review has examined how bipolar disorder medications interact with the gut microbiome, revealing important links between treatment response and gut microbial composition. Researchers analyzed 12 studies comparing…
Hallucinogens Linked to Milder PTSD
Summary: In a unique real-world study, researchers examined the psychological effects of trauma on survivors of the October 7 Nova Festival attack in Israel, focusing on their use of mind-altering…
Boosting Ketamine’s Antidepressant Effects to Last Two Months
Summary: Ketamine is a fast-acting antidepressant that can relieve symptoms of major depressive disorder (MDD) within hours, even in treatment-resistant cases. However, its effects typically last only a week, and…