Summary: Psilocybin use in the U.S. has risen sharply across all age groups since 2019, coinciding with increasing legalization and interest in its therapeutic potential. A new study reveals a…
Tag: psychopharmacology
Psychedelics Linked to Visual Echoes
Summary: As psychedelics gain traction in mental health treatment, questions remain about their long-term effects. A new study followed individuals self-administering psychedelics and found that while some experienced lingering visual…
LSD-Inspired Drug Reverses Psychosis Brain Damage Without Hallucinations
Summary: A new LSD-derived compound called JRT shows promise for treating schizophrenia and other brain disorders without inducing hallucinations. Developed by researchers who altered just two atoms in LSD’s structure,…
How Psilocybin Lifts Mood Without the Hallucinogenic Trip
Summary: Researchers have uncovered two key brain mechanisms—specific neurons and a serotonin receptor—that help explain how psilocybin produces long-lasting antidepressant effects. Their study identified pyramidal tract neurons in the medial…
Psychedelics May Enhance Intimacy, Attraction, and Sexual Expression
Summary: In the first study of its kind, researchers found that psychedelic use can positively affect sexuality, romantic relationships, and gender expression. Surveying nearly 600 users of substances like psilocybin,…
SSRIs May Speed Up Cognitive Decline
Summary: A new study based on data from 18,740 dementia patients suggests that antidepressants may accelerate cognitive decline. Researchers found that patients taking antidepressants, particularly SSRIs like escitalopram, citalopram, and…
Repurposed Blood Pressure Drug May Treat ADHD
Summary: A new study suggests that amlodipine, a widely used blood pressure medication, could help manage ADHD symptoms. Researchers tested five potential drugs in rats bred for ADHD-like behaviors, and…
How Ketamine Binds to Brain Receptors to Alter Mood
Summary: New research sheds light on how ketamine affects the brain by targeting a specific NMDA receptor subtype, GluN1-2B-2D. Scientists used electron cryo-microscopy to capture how ketamine binds to this…
Prozac Shows Promise in Fighting Infections & Sepsis
Summary: New research suggests that fluoxetine, commonly used as an antidepressant, may also help protect against infections and sepsis. Scientists found that the drug has antimicrobial properties and helps regulate…
Ketamine Reduces “Giving Up” by Targeting Brain Support Cells
Summary: Researchers have found that ketamine’s antidepressant effects target astroglia, a type of brain support cell, rather than neurons, challenging conventional views. Using zebrafish, scientists observed that ketamine suppressed the…
