How Chocolate’s Puckering Taste May Stimulate the Brain

Summary: Japanese researchers have uncovered how the astringent “bite” of cocoa flavanols can activate the brain—even though little of the compound enters the bloodstream. In mice, the sensation of astringency…

AI Reveals Bitter Taste Receptors’ Hidden Role in Gut-Brain Health

Summary: Researchers used AlphaFold3, the latest AI-based protein modeling system, to predict the structures of all 25 known human bitter taste receptors (T2Rs). Compared with AlphaFold2, AF3 consistently generated more…