Boosting Wnt Signaling Reverses APOE4 Alzheimer’s Damage

Summary: MIT neuroscientists discovered that the APOE4 gene variant suppresses critical Wnt signaling in oligodendrocytes, trapping essential fatty acids inside toxic lipid droplets rather than deploying them as protective myelin…

Genetic Risk for Anorexia May Begin Outside the Brain

Summary: A new genetic study reveals that individuals with severe anorexia nervosa are nearly four times more likely to carry rare, damaging mutations in PLIN4, a gene primarily expressed in…