Summary: Researchers have discovered that the youth-associated protein TIMP2 plays a critical role in maintaining the healthy function of microglia, the brain’s primary immune cells. Supplementing this protein in aged…
Category: microglia
Microglial State Transitions Dictate Alzheimer’s
Summary: Researchers unmasked a critical cellular transition that dictates whether Alzheimer’s disease pathology triggers clinical dementia. The research analyzed brain tissue from older adults, including cognitively healthy centenarians, to map…
Microglia’s Role in Controlling Anxiety and OCD
Summary: A new study reveals how microglia can regulate anxiety and obsessive-compulsive spectrum disorder (OCSD) behaviors. Traditionally overlooked in favor of neurons, specific microglia populations were found to both stimulate…
Unique Microglia Subset Crucial for Cognitive Functioning
Summary: A new study discovered not all microglia are the same, challenging existing beliefs. A unique subset of these cells, the ARG1+microglia, important for proper cognitive functions, were identified in…
