Summary: Adults taking high doses of amphetamine-based medications for ADHD, such as Adderall, face a five-fold increased risk of developing psychosis or mania. The risk was highest for those taking…
Category: psychopharmacology
Knowingly Taking Placebos Reduces Stress and Anxiety
Summary: Researchers have discovered that nondeceptive placebos—placebos given with the full knowledge that they are placebos—can effectively manage stress, even when administered remotely. In a two-week randomized controlled trial, participants…
High-Dose Psilocybin Shows Potential as an Antidepressant Treatment
Summary: A meta-analysis suggests that high doses of psilocybin may alleviate depressive symptoms similarly to the SSRI drug escitalopram. While the effect size was small, psilocybin outperformed placebo in clinical…
Mind-Bending: Psilocybin Reshapes Brain Networks for Weeks
Summary: A new study reveals that psilocybin, the active compound in magic mushrooms, temporarily disrupts brain networks involved in introspective thinking, like daydreaming and memory. These changes persist for weeks,…
Surge in Microdosing Interest Linked to Relaxed Drug Policies
Summary: A new study reveals a 1250% increase in Google searches for micro dosing from 2015 to 2023, driven by relaxed regulations on cannabis and psychedelics. The research shows policy…
MDMA Variants Show Promise for Safer Psychotherapy
Summary: Researchers developed three new MDMA variants (ODMA, TDMA, and SeDMA) that retain the therapeutic benefits while reducing side effects. These compounds affect mood-regulating brain structures similarly to MDMA but…
Antidepressants Impact Brain Development – Neuroscience News
Summary: Using antidepressants during pregnancy, specifically fluoxetine (found in Prozac and Sarafem), can significantly affect a child’s brain development, particularly in the prefrontal cortex, potentially increasing the risk of mental…
Psychoactive Ibogaine and Magnesium Show Promise for PTSD
Summary: Ibogaine, a plant-based psychoactive drug combined with magnesium, effectively reduces PTSD, anxiety, and depression in veterans with traumatic brain injuries (TBI). The study, involving 30 U.S. special forces veterans,…
Unraveling Psychedelics’ Potential in Mental Health
Summary: Research delves into the potential of psychedelics like psilocybin for treating psychiatric disorders. Studies show varying effects of psilocybin on fear learning in rats and mice, dependent on sex…
Psilocybin Microdosing Promising for Mental Health Disorders
Summary: Researchers delve into the therapeutic potential of psilocybin microdosing, exploring its influence on stress resilience and compulsive behaviors in rats. While high-dose psilocybin therapy has been scrutinized for psychiatric…
