Summary: Researchers have uncovered shared biological mechanisms across major psychiatric disorders by analyzing postmortem brain samples from the dorsolateral prefrontal cortex. Instead of looking at gene expression broadly, they zoomed…
Tag: Dopamine
Vitamin B1 Derivative Sparks Dopamine, Boosts Wakefulness
Summary: Thiamine derivatives, once developed to treat nutrient deficiencies, are now being explored for their potential effects on brain function and energy. A new study shows that TTFD, a thiamine…
Dopamine Signals Teach the Brain to Unlearn Fear
Summary: A new study reveals that dopamine release along a specific brain circuit helps extinguish fear by activating reward-related neurons in the amygdala. Researchers showed that dopamine from the ventral…
Potential Depression Risk Linked to Ozempic-Like Drugs
Summary: A new international study reveals a possible connection between GLP1 receptor agonists—used in drugs like Ozempic—and increased risk of depression and suicidal ideation, especially in people with low dopamine…
Elevated Dopamine in Cannabis Users May Explain Psychosis Risk
Summary: New research reveals that people with cannabis use disorder (CUD) have elevated dopamine levels in a brain region associated with psychosis, such as schizophrenia. This may help explain why…
Dopamine Clock May Drive Bipolar Mood Swings
Summary: New research suggests that mood swings in bipolar disorder are regulated by two clocks: the body’s 24-hour circadian rhythm and a dopamine-based clock that influences alertness. When these clocks…
Targeting Reward Pathways to Treat Depression
Summary: New research highlights how the brain’s reward-learning system can guide personalized treatments for depression. By studying two brain signals, expected value and prediction error, researchers identified markers that predict…
Dopamine and Serotonin Drive Emotional Word Processing
Summary: Researchers have uncovered how neurotransmitters in the brain respond to the emotional content of language, shedding light on the intersection of emotion, cognition, and communication. Using advanced techniques, the…
Dopamine Plays Key Role in the Heart’s Stress Response
Summary: Researchers have discovered how stress-induced cardiovascular changes are controlled by the brain. Experiments in rats show that activating the lateral habenula, a stress-sensitive brain region, triggers changes in heart…
Immune System Gene Linked to Hyperactivity, ADHD and Autism
Summary: Researchers have uncovered a link between the immune gene regulator STAT1 and hyperactive behaviors in mice, offering new insights into neurodevelopmental disorders like autism and ADHD. STAT1, vital for…
