Study uncovers multiple molecular subgroups in liver cancer with most aggressive driving clinical outcomes

Credit: Journal of Hepatology (2024). DOI: 10.1016/j.jhep.2024.05.017 A study led by clinician-scientists and scientists from the National Cancer Centre Singapore (NCCS) and A*STAR’s Genome Institute of Singapore (GIS) has discovered…

Human muscle map reveals how we try to fight effects of aging at cellular and molecular levels

Skeletal muscle fibers. Credit: Berkshire Community College Bioscience Image Library / Public domain How muscle changes with aging and tries to fight its effects is now better understood at the…

Learning and Memory Formation’s Molecular Basis

Summary: Researchers developed a new platform to explore dendritic translation’s role in memory formation and its implications for intellectual disorders. By employing a novel method named TurboID, researchers uncovered a…

Powering Brain Repair: Mitochondria Key to Neurogenesis

Summary: Researchers made a groundbreaking discovery about the maturation process of adult-born neurons in the brain, highlighting the critical role of mitochondrial fusion in these cells. Their study shows that…

Biological mechanism discovered that could lead to new treatments for neurological disorders and cancers

Credit: Pixabay/CC0 Public Domain The lab of Yongchao C. Ma, Ph.D., at Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago has discovered a…

Genetic causes of cerebral palsy uncovered through whole-genome sequencing

Credit: Unsplash/CC0 Public Domain A Canadian-led study has identified genes which may be partially responsible for the development of cerebral palsy. Cerebral palsy (CP), a condition that affects the development…

Hereditary Alzheimer’s Transmitted Via Bone Marrow Transplants

Summary: Alzheimer’s disease, traditionally seen as a brain-centric condition, may have systemic origins and can be accelerated through bone marrow transplants from donors with familial Alzheimer’s to healthy mice. A…

THC Metabolism Could Influence Cannabis Use Disorder Risk

Summary: Researchers linked differences in THC metabolism to varying effects of cannabis use and the risk of developing Cannabis Use Disorder (CUD). The study, which included young adults with and…

Epigenetics is of critical importance in autoimmune-related skin diseases, says study

Credit: Lingyu Gao, Qianjin Lu The central dogma proposed that genetic information predominantly transfers from DNA to RNA during gene expression to make a functional product protein. This absolute theory…

New review on p53 biology and reactivation in blood cancers

A simplified scheme of p53 regulation in cells upon stress and the drugs currently evaluated in clinical trials for p53 reactivation for improved therapy in MDS and AML. Credit: Biomarker…